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NCT03535688 · ClinicalTrials.gov registry record · Phase 2
D-cycloserine for the Treatment of Chronic, Refractory Low Back Pain
A Phase 2 study, sponsored by Northwestern University.
- Terminated
- Registry status
- Phase 2
- Development phase
- 203
- Enrollment target
NCT03535688: Clinical Trial Phase 2 study, sponsored by Northwestern University.
NCT03535688 is a Phase 2 study that was terminated before completion, run by Northwestern University. The registered enrollment target is 203 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (53% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03535688, a Phase 2 study, was terminated before completion, sponsored by Northwestern University.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 203 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the efficacy and safety of D-cycloserine versus placebo in relieving the signs and symptoms of patients with chronic lower back pain.
Primary Outcome
Mean pain levels will be assessed at study baseline and compared to mean pain levels at Week 12 (study efficacy endpoint). Pain will be assessed using an 11-point NRS scale.
Interventions
- DRUG Placebo
- DRUG D-cycloserine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 203 participants |
| Start Date | 2018-03-30 |
| Est. Completion | 2024-02-07 |
| Phase | Phase 2 |
Why NCT03535688 stopped before completion
NCT03535688 is an interventional study that assigns participants to a tested intervention. The registered 203 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (53% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT03535688 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03535688 about?
NCT03535688 is a clinical study titled "D-cycloserine for the Treatment of Chronic, Refractory Low Back Pain". The purpose of this study is to evaluate the efficacy and safety of D-cycloserine versus placebo in relieving the signs and symptoms of patients with chronic lower back pain.
What is the current status of trial NCT03535688?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 203 participants. The study started on 2018-03-30. Estimated completion is 2024-02-07.
What interventions are being tested in trial NCT03535688?
The interventions under investigation include: Placebo (DRUG), D-cycloserine (DRUG).
Who is sponsoring clinical trial NCT03535688?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03535688's enrollment target sits among peer trials
203 301st of 2000 higher than 1,700 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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