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NCT03530397 · ClinicalTrials.gov registry record · Phase 1

A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors

A Phase 1 study of Selected Advanced Solid Tumors, sponsored by MedImmune.

Active
Registry status
Phase 1
Development phase
401
Enrollment target
20
Study locations

NCT03530397 is a Phase 1 study of Selected Advanced Solid Tumors that is active but no longer recruiting, run by MedImmune. The registered enrollment target is 401 participants. The trial reports 20 study locations across 7 states.

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The verdict

NCT03530397, a Phase 1 study of Selected Advanced Solid Tumors, is active but no longer recruiting, sponsored by MedImmune.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
401 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to evaluate MEDI5752 and carboplatin and pemetrexed or paclitaxel or nab-paclitaxel in adult subjects with advanced solid tumors, when administered as a single agent or combined with chemotherapy.

Interventions

  • BIOLOGICAL Pembrolizumab
  • DRUG Carboplatin
  • DRUG Pemetrexed
  • BIOLOGICAL MEDI5752
  • DRUG Paclitaxel or Nab-Paclitaxel

Study Locations (20)

Other

  • Research Site - Melbourne
  • Research Site - Melbourne
  • Research Site - Randwick
  • Research Site - Bordeaux
  • Research Site - Lyon
  • Research Site - Villejuif
  • Research Site - Meldola
  • Research Site - Naples
  • Research Site - Ravenna
  • Research Site - Roma
  • Research Site - Amsterdam
  • Research Site - Lisbon
  • Research Site - Porto

Tennessee

  • Research Site - Chattanooga
  • Research Site - Nashville

Michigan

  • Research Site - Detroit

New York

  • Research Site - New York

North Carolina

  • Research Site - Chapel Hill

Rhode Island

  • Research Site - Providence

Virginia

  • Research Site - Fairfax

Trial Details

FieldValue
Enrollment Target 401 participants
Start Date 2018-04-24
Est. Completion 2025-12-30
Phase Phase 1

Sponsor

MedImmune

210 total trials

What the Registry Record Tells You About NCT03530397

The ClinicalTrials.gov registry entry for NCT03530397 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 401 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is MedImmune, which has 210 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Selected Advanced Solid Tumors appearing as the primary indexed condition, and to 5 interventions - of which Pembrolizumab is the first listed.

NCT03530397 reports 20 study locations spanning 7 distinct geographic areas - top geographies include Other, Tennessee, Michigan.

Frequently Asked Questions

What is clinical trial NCT03530397 about?

NCT03530397 is a clinical study titled "A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors". The purpose of this study is to evaluate MEDI5752 and carboplatin and pemetrexed or paclitaxel or nab-paclitaxel in adult subjects with advanced solid tumors, when administered as a single agent or combined with chemotherapy.

What is the current status of trial NCT03530397?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 401 participants. The study started on 2018-04-24. Estimated completion is 2025-12-30.

What conditions does trial NCT03530397 study?

This clinical trial studies the following conditions: Selected Advanced Solid Tumors.

What interventions are being tested in trial NCT03530397?

The interventions under investigation include: Pembrolizumab (BIOLOGICAL), Carboplatin (DRUG), Pemetrexed (DRUG), MEDI5752 (BIOLOGICAL), Paclitaxel or Nab-Paclitaxel (DRUG).

Who is sponsoring clinical trial NCT03530397?

This trial is sponsored by MedImmune, which has 210 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03530397 being conducted?

This trial has 20 study locations across Michigan, New York, North Carolina, Rhode Island, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.