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NCT03528486 · ClinicalTrials.gov registry record · NA
Interventions to Attenuate Cognitive Decline: Keys to Staying Sharp
A NA study, sponsored by University of South Florida.
- Completed
- Registry status
- NA
- Development phase
- 268
- Enrollment target
NCT03528486 is a NA study that has completed, run by University of South Florida. The registered enrollment target is 268 participants.
The verdict
NCT03528486, a NA study, has completed, sponsored by University of South Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 268 participants
- Enrollment target
Study Summary
Different cognitive intervention approaches have been developed to attenuate decline (e.g., cognitive engagement, training, or stimulation), but it is not clear which approaches are efficacious. It is also not clear when, along the continuum of normal cognitive aging to mild cognitive impairment (MCI-a transitional stage before dementia onset), it is most efficacious to intervene. This randomized clinical trial will determine the efficacy of a novel cognitive engagement intervention approach (music training) as compared to cognitive stimulation (which will serve as a stringent, active control). Grounded in theory, the central hypothesis is that interventions enhancing central auditory processing (CAP), a strong, longitudinal predictor of MCI and dementia, will improve cognition. Music training is increasingly recognized as a feasible means to attenuate age-related cognitive decline. Prior research and preliminary data suggest that intense piano training enhances CAP and is likely more effective than cognitive stimulation. Correlational studies indicate superior CAP, executive function, and other cognitive abilities for adults with formal music training compared to non-musicians. The specific aims of the study are to examine the efficacy of music training relative to cognitive stimulation (active controls) to improve CAP, cognition, and everyday function among older adults with and without MCI. The efficacy of music training will be established and moderating effects of MCI status will be examined. The proposed study further aims to elucidate the underlying mechanisms of effective cognitive intervention approaches by exploring mediators of training gains. The proposed study is the first phase II randomized trial of music training to enhance older adults' cognition. Mediation analyses will elucidate the underlying mechanisms of intervention effects.
Interventions
- BEHAVIORAL Music Training I
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 268 participants |
| Start Date | 2018-01-29 |
| Est. Completion | 2021-12-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03528486
The ClinicalTrials.gov registry entry for NCT03528486 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 268 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of South Florida, which has 252 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Music Training I is the first listed.
NCT03528486 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03528486 about?
NCT03528486 is a clinical study titled "Interventions to Attenuate Cognitive Decline: Keys to Staying Sharp". Different cognitive intervention approaches have been developed to attenuate decline (e.g., cognitive engagement, training, or stimulation), but it is not clear which approaches are efficacious. It is also not clear when, along the continuum of normal cognitive aging to mild cognitive impairment (MC...
What is the current status of trial NCT03528486?
This trial is currently completed. It is a NA study. The enrollment target is 268 participants. The study started on 2018-01-29. Estimated completion is 2021-12-30.
What interventions are being tested in trial NCT03528486?
The interventions under investigation include: Music Training I (BEHAVIORAL).
Who is sponsoring clinical trial NCT03528486?
This trial is sponsored by University of South Florida, which has 252 total clinical trials registered on ClinicalTrials.gov.
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