Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03526536 · ClinicalTrials.gov registry record · Phase 4

Pilot: Insulin Sensitivity/Management in Hyperglycemic Patients in Perioperative Period ESRD/Non-ESRD

A Phase 4 study, sponsored by State University of New York - Downstate Medical Center.

Terminated
Registry status
Phase 4
Development phase
40
Enrollment target

NCT03526536: Clinical Trial Phase 4 study, sponsored by State University of New York - Downstate Medical Center.

NCT03526536 is a Phase 4 study that was terminated before completion, run by State University of New York - Downstate Medical Center. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03526536, a Phase 4 study, was terminated before completion, sponsored by State University of New York - Downstate Medical Center.

TERMINATED
Registry status
Phase 4
Development phase
40 participants
Enrollment target

Study Summary

This study is for people with diabetes who have either healthy kidneys or who have end stage renal disease (ESRD) and are on hemodialysis that are having surgery. This research will help increase our knowledge about how having diseased kidneys and being on hemodialysis changes how the body responds to insulin. In the time period directly before, during, and after surgery, maintenance of blood sugar within normal physiological range is essential. When patients come for surgery and have an elevated blood sugar, it is up to each individual physician to decide on the right amount of insulin to treat them. Currently, there are many different protocols across the country to treat elevated blood sugar; however, there is no one specific protocol to treat elevated blood sugar at SUNY Downstate Medical Center at this time. In this study, the investigators will evaluate the change in blood sugar following insulin administration to determine whether there is a significantly different response between ESRD and non-ESRD patients. The results of the study will help develop safer practice guidelines to patients with ESRD with an elevated blood sugar while they are having surgery.

Primary Outcome

Change in blood glucose level measures using a glucometer (Nova Biomedical, Waltham, MA. USA)

Interventions

  • DRUG IV Novolin R human insulin

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2018-05-01
Est. Completion 2020-09-03
Phase Phase 4

Why NCT03526536 stopped before completion

NCT03526536 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 1 intervention - of which IV Novolin R human insulin is the first listed.

NCT03526536 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03526536 about?

NCT03526536 is a clinical study titled "Pilot: Insulin Sensitivity/Management in Hyperglycemic Patients in Perioperative Period ESRD/Non-ESRD". This study is for people with diabetes who have either healthy kidneys or who have end stage renal disease (ESRD) and are on hemodialysis that are having surgery. This research will help increase our knowledge about how having diseased kidneys and being on hemodialysis changes how the body responds ...

What is the current status of trial NCT03526536?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2018-05-01. Estimated completion is 2020-09-03.

What interventions are being tested in trial NCT03526536?

The interventions under investigation include: IV Novolin R human insulin (DRUG).

Who is sponsoring clinical trial NCT03526536?

This trial is sponsored by State University of New York - Downstate Medical Center, which has 18 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03526536's enrollment target sits among peer trials

40 1397th of 2000 higher than 533 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01306019 · 40 participants · Phase 1

    Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)

  • NCT01608152 · 40 participants

    Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors

  • NCT01668082 · 40 participants · NA

    An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection

  • NCT02015013 · 40 participants · Phase 2

    Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03526536, the US trial registry maintained by the National Library of Medicine. NCT03526536 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.