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NCT03525574 · ClinicalTrials.gov registry record · Phase 3
A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy
A Phase 3 study, sponsored by Vertex Pharmaceuticals Incorporated.
- Completed
- Registry status
- Phase 3
- Development phase
- 507
- Enrollment target
NCT03525574 is a Phase 3 study that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 507 participants.
The verdict
NCT03525574, a Phase 3 study, has completed, sponsored by Vertex Pharmaceuticals Incorporated.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 507 participants
- Enrollment target
Study Summary
The study evaluates the long-term safety and tolerability of VX-445 in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects with cystic fibrosis (CF) who are homozygous or heterozygous for the F508del mutation
Interventions
- DRUG IVA
- DRUG ELX/TEZ/IVA
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 507 participants |
| Start Date | 2018-10-09 |
| Est. Completion | 2023-01-09 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03525574
The ClinicalTrials.gov registry entry for NCT03525574 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 507 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vertex Pharmaceuticals Incorporated, which has 191 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which IVA is the first listed.
NCT03525574 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03525574 about?
NCT03525574 is a clinical study titled "A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy". The study evaluates the long-term safety and tolerability of VX-445 in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects with cystic fibrosis (CF) who are homozygous or heterozygous for the F508del mutation
What is the current status of trial NCT03525574?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 507 participants. The study started on 2018-10-09. Estimated completion is 2023-01-09.
What interventions are being tested in trial NCT03525574?
The interventions under investigation include: IVA (DRUG), ELX/TEZ/IVA (DRUG).
Who is sponsoring clinical trial NCT03525574?
This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.
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