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NCT03524690 · ClinicalTrials.gov registry record · NA
Effects of Severe Negative Energy Balance on Inflammation
A NA study, sponsored by United States Army Research Institute of Environmental Medicine.
- Completed
- Registry status
- NA
- Development phase
- 13
- Enrollment target
NCT03524690: Completed NA study, sponsored by United States Army Research Institute of Environmental Medicine.
NCT03524690 is a NA study that has completed, run by United States Army Research Institute of Environmental Medicine. The registered enrollment target is 13 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03524690, a NA study, has completed, sponsored by United States Army Research Institute of Environmental Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 13 participants
- Enrollment target
Study Summary
The effects of prolonged negative energy balance, commonly observed in sustained military training and combat operations, on systemic inflammatory responses has not been determined. To define the putative role of energy balance on inflammation and its downstream effects, we will conduct a controlled laboratory study that simulates extensive physiological stressors to determine if inflammation is exacerbated by underfeeding. This design will test the hypothesis that maintaining energy balance will attenuate systemic inflammation and its potential negative effects on whole-body metabolic homeostasis in response to physiological stressors.
Primary Outcome
Assessed using blood assays.
Interventions
- DIETARY_SUPPLEMENT Energy Balance
- DIETARY_SUPPLEMENT Negative Energy Balance
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2019-02-13 |
| Est. Completion | 2019-10-08 |
| Phase | NA |
What the finished NCT03524690 record still lists
NCT03524690 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Energy Balance is the first listed.
NCT03524690 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03524690 about?
NCT03524690 is a clinical study titled "Effects of Severe Negative Energy Balance on Inflammation". The effects of prolonged negative energy balance, commonly observed in sustained military training and combat operations, on systemic inflammatory responses has not been determined. To define the putative role of energy balance on inflammation and its downstream effects, we will conduct a controlled...
What is the current status of trial NCT03524690?
This trial is currently completed. It is a NA study. The enrollment target is 13 participants. The study started on 2019-02-13. Estimated completion is 2019-10-08.
What interventions are being tested in trial NCT03524690?
The interventions under investigation include: Energy Balance (DIETARY_SUPPLEMENT), Negative Energy Balance (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03524690?
This trial is sponsored by United States Army Research Institute of Environmental Medicine, which has 59 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03524690's enrollment target sits among peer trials
13 1911th of 2000 higher than 88 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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