Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03520569 · ClinicalTrials.gov registry record · Early Phase 1
Effect of Hyperglycemia on Microvascular Perfusion in Healthy Adults
A Early Phase 1 study, sponsored by University of Virginia.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 15
- Enrollment target
NCT03520569: Completed Early Phase 1 study, sponsored by University of Virginia.
NCT03520569 is a Early Phase 1 study that has completed, run by University of Virginia. The registered enrollment target is 15 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (72% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03520569, a Early Phase 1 study, has completed, sponsored by University of Virginia.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 15 participants
- Enrollment target
Study Summary
The investigators are studying the effects of Hyperglycemia on vascular function and insulin sensitivity on healthy adults
Primary Outcome
Flow mediated dilation measures the change in brachial diameter in response to 5 minutes of ischemia using B-mode ultrasound. It provides an index of nitric oxide generation by the endothelium .
Interventions
- DRUG Insulin
- DRUG Octreotide
- DRUG Dextrose 20% solution
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2019-02-04 |
| Est. Completion | 2021-04-01 |
| Phase | Early Phase 1 |
What the finished NCT03520569 record still lists
NCT03520569 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (72% lower).
The record links to 0 conditions, and to 3 interventions - of which Insulin is the first listed.
NCT03520569 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03520569 about?
NCT03520569 is a clinical study titled "Effect of Hyperglycemia on Microvascular Perfusion in Healthy Adults". The investigators are studying the effects of Hyperglycemia on vascular function and insulin sensitivity on healthy adults
What is the current status of trial NCT03520569?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 15 participants. The study started on 2019-02-04. Estimated completion is 2021-04-01.
What interventions are being tested in trial NCT03520569?
The interventions under investigation include: Insulin (DRUG), Octreotide (DRUG), Dextrose 20% solution (DRUG).
Who is sponsoring clinical trial NCT03520569?
This trial is sponsored by University of Virginia, which has 449 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03520569's enrollment target sits among peer trials
15 1404th of 2000 higher than 527 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01889381 · 15 participants · Phase 2
Human Craniomaxillofacial Allotransplantation
- NCT02530073 · 15 participants · NA
Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) for CDH
- NCT02535936 · 15 participants · NA
Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy
- NCT02918474 · 15 participants · NA
Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI