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NCT03520504 · ClinicalTrials.gov registry record · Phase 1
Study of Proton Radiation to the Brain and Spinal Cord for Patients With Leptomeningeal Metastases
A Phase 1 study of Leptomeningeal Metastases, sponsored by Memorial Sloan Kettering Cancer Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
- 8
- Study locations
NCT03520504: Completed Phase 1 study of Leptomeningeal Metastases, sponsored by Memorial Sloan Kettering Cancer Center.
NCT03520504 is a Phase 1 study of Leptomeningeal Metastases that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 24 participants, below the 58-participant average among 3 other Leptomeningeal Metastases trials with a reported enrollment target (59% lower). The trial reports 8 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03520504, a Phase 1 study of Leptomeningeal Metastases, has completed, sponsored by Memorial Sloan Kettering Cancer Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
- 8
- Study locations
Study Summary
The purpose of this study is to find the safest and most effective dose for delivering proton beam to the space containing CSF, brain, and spinal cord, in treating leptomeningeal metastases. The researchers think that using proton beam radiation to treat the space containing CSF, brain, and spinal cord, instead of treating only the areas where the metastasized tumor cells are causing symptoms, would improve the treatment of this disease.
Primary Outcome
will be assessed by physician-graded CTCEAv4
Conditions Studied
Interventions
- RADIATION Proton craniospinal irradiation (CSI)
Study Locations (8)
New York
- Memorial Sloan Kettering Commack - Commack
- Memorial Sloan Kettering Westchester - Harrison
- Memorial Sloan Kettering Cancer Center - New York
- Memorial Sloan Kettering Rockville Centre - Rockville Centre
- Memorial Sloan Kettering Nassau - Uniondale
New Jersey
- Memorial Sloan Kettering Basking Ridge - Basking Ridge
- Memorial Sloan Kettering Monmouth - Middletown
- Memorial Sloan Kettering Bergen - Montvale
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2018-04-26 |
| Est. Completion | 2022-12-22 |
| Phase | Phase 1 |
What the finished NCT03520504 record still lists
NCT03520504 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 58-participant average among 3 other Leptomeningeal Metastases trials with a reported enrollment target (59% lower).
The record links to 1 condition, with Leptomeningeal Metastases appearing as the primary indexed condition, and to 1 intervention - of which Proton craniospinal irradiation (CSI) is the first listed.
NCT03520504 lists 8 locations in 2 states (New York, New Jersey).
Frequently Asked Questions
What is clinical trial NCT03520504 about?
NCT03520504 is a clinical study titled "Study of Proton Radiation to the Brain and Spinal Cord for Patients With Leptomeningeal Metastases". The purpose of this study is to find the safest and most effective dose for delivering proton beam to the space containing CSF, brain, and spinal cord, in treating leptomeningeal metastases. The researchers think that using proton beam radiation to treat the space containing CSF, brain, and spinal c...
What is the current status of trial NCT03520504?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2018-04-26. Estimated completion is 2022-12-22.
What conditions does trial NCT03520504 study?
This clinical trial studies the following conditions: Leptomeningeal Metastases.
What interventions are being tested in trial NCT03520504?
The interventions under investigation include: Proton craniospinal irradiation (CSI) (RADIATION).
Who is sponsoring clinical trial NCT03520504?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03520504 being conducted?
This trial has 8 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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