Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03513848 · ClinicalTrials.gov registry record · NA

Morning Light Treatment at Home to Reduce PTSD Symptoms

A NA study, sponsored by Rush University Medical Center.

Completed
Registry status
NA
Development phase
15
Enrollment target

NCT03513848: Completed NA study, sponsored by Rush University Medical Center.

NCT03513848 is a NA study that has completed, run by Rush University Medical Center. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03513848, a NA study, has completed, sponsored by Rush University Medical Center.

COMPLETED
Registry status
NA
Development phase
15 participants
Enrollment target

Study Summary

There is evidence that some of the circadian photoreceptors, the intrinsically photosensitive retinal ganglion cells (ipRGCs), project directly to the amygdala, an area of the brain implicated in PTSD. Thus, a self-administered morning light treatment at home (shifts clock earlier and stimulates ipRGCs) may be a potentially efficacious adjunctive strategy for reducing PTSD symptoms. This study will test a 4 week daily 1 hour morning light treatment (active vs placebo) in individuals with PTSD. Outcome measures include measures of PTSD and depression.

Primary Outcome

The PTSD Checklist for DSM-5 (PCL-5) is the gold standard measure of PTSD symptom severity. Range: 0-80. Higher scores indicate worse outcomes. We will assess change in PCL-5 scores over 4 weeks of treatment \[Week 2 through Week 6 of the study\].

Interventions

  • DEVICE Retimer
  • DEVICE Retimer placebo

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2016-04-01
Est. Completion 2018-06-28
Phase NA
Rush University Medical Center

320 total trials

What the finished NCT03513848 record still lists

NCT03513848 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Retimer is the first listed.

NCT03513848 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03513848 about?

NCT03513848 is a clinical study titled "Morning Light Treatment at Home to Reduce PTSD Symptoms". There is evidence that some of the circadian photoreceptors, the intrinsically photosensitive retinal ganglion cells (ipRGCs), project directly to the amygdala, an area of the brain implicated in PTSD. Thus, a self-administered morning light treatment at home (shifts clock earlier and stimulates ipR...

What is the current status of trial NCT03513848?

This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2016-04-01. Estimated completion is 2018-06-28.

What interventions are being tested in trial NCT03513848?

The interventions under investigation include: Retimer (DEVICE), Retimer placebo (DEVICE).

Who is sponsoring clinical trial NCT03513848?

This trial is sponsored by Rush University Medical Center, which has 320 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03513848's enrollment target sits among peer trials

15 1881st of 2000 higher than 92 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01889381 · 15 participants · Phase 2

    Human Craniomaxillofacial Allotransplantation

  • NCT02530073 · 15 participants · NA

    Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) for CDH

  • NCT02535936 · 15 participants · NA

    Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy

  • NCT02918474 · 15 participants · NA

    Decision Making Tool in Supporting Decision Making in Contralateral Prophylactic Mastectomy in Patients With Newly Diagnosed Breast Cancer

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03513848, the US trial registry maintained by the National Library of Medicine. NCT03513848 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.