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NCT03509753 · ClinicalTrials.gov registry record · NA
Prebiotic Fiber to Prevent Pathogen Colonization in the ICU
A NA study, sponsored by Columbia University.
- Completed
- Registry status
- NA
- Development phase
- 22
- Enrollment target
NCT03509753: Completed NA study, sponsored by Columbia University.
NCT03509753 is a NA study that has completed, run by Columbia University. The registered enrollment target is 22 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03509753, a NA study, has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- NA
- Development phase
- 22 participants
- Enrollment target
Study Summary
This is a pilot trial testing enteral feeds that are high versus low in prebiotic fiber in 20 critically ill adults. The long-term goal is to determine the efficacy of fiber for the prevention of pathogen colonization/infection in the ICU.
Primary Outcome
An untargeted hierarchical linear discriminant analysis effect size algorithm (LEfSe) will be used to test for within-individual taxonomic differences comparing baseline to Day 3 in the high fiber group as it is an established method for identifying differences in bacterial taxa between any two groups. For those taxa which are significantly altered on LEfSe, the relative change in the high fiber group versus the relative change in the low fiber group will be computed using a rank-sum test.
Interventions
- DIETARY_SUPPLEMENT High Fiber
- DIETARY_SUPPLEMENT Low Fiber
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2018-08-16 |
| Est. Completion | 2019-08-01 |
| Phase | NA |
What the finished NCT03509753 record still lists
NCT03509753 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which High Fiber is the first listed.
NCT03509753 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03509753 about?
NCT03509753 is a clinical study titled "Prebiotic Fiber to Prevent Pathogen Colonization in the ICU". This is a pilot trial testing enteral feeds that are high versus low in prebiotic fiber in 20 critically ill adults. The long-term goal is to determine the efficacy of fiber for the prevention of pathogen colonization/infection in the ICU.
What is the current status of trial NCT03509753?
This trial is currently completed. It is a NA study. The enrollment target is 22 participants. The study started on 2018-08-16. Estimated completion is 2019-08-01.
What interventions are being tested in trial NCT03509753?
The interventions under investigation include: High Fiber (DIETARY_SUPPLEMENT), Low Fiber (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03509753?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03509753's enrollment target sits among peer trials
22 1756th of 2000 higher than 239 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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