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NCT03505723 · ClinicalTrials.gov registry record · Phase 3
PeriOperative ISchemic Evaluation-3 Trial
A Phase 3 study, sponsored by Population Health Research Institute.
- Completed
- Registry status
- Phase 3
- Development phase
- 9,535
- Enrollment target
NCT03505723: Completed Phase 3 study, sponsored by Population Health Research Institute.
NCT03505723 is a Phase 3 study that has completed, run by Population Health Research Institute. The registered enrollment target is 9,535 participants, above the 771-participant average among 15,282 other Phase 3 trials with a reported enrollment target (1137% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03505723, a Phase 3 study, has completed, sponsored by Population Health Research Institute.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 9,535 participants
- Enrollment target
Study Summary
This study is a multicentre, international, randomized controlled trial of tranexamic acid (TXA) versus placebo and, using a partial factorial design, of a perioperative hypotension-avoidance versus hypertension-avoidance strategy.
Primary Outcome
Number of patients who have at least one of the following: life-threatening bleeding, major bleeding, and critical organ bleeding
Interventions
- DRUG Tranexamic Acid
- DRUG Placebo (Saline)
- OTHER Perioperative hypotension-avoidance strategy
- OTHER Perioperative hypertension-avoidance strategy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9,535 participants |
| Start Date | 2018-06-27 |
| Est. Completion | 2023-02-03 |
| Phase | Phase 3 |
What the finished NCT03505723 record still lists
NCT03505723 is an interventional study that assigns participants to a tested intervention. Its 9,535 participants enrollment target places it among the larger protocols in the corpus, above the 771-participant average among 15,282 other Phase 3 trials with a reported enrollment target (1137% higher).
The record links to 0 conditions, and to 4 interventions - of which Tranexamic Acid is the first listed.
NCT03505723 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03505723 about?
NCT03505723 is a clinical study titled "PeriOperative ISchemic Evaluation-3 Trial". This study is a multicentre, international, randomized controlled trial of tranexamic acid (TXA) versus placebo and, using a partial factorial design, of a perioperative hypotension-avoidance versus hypertension-avoidance strategy.
What is the current status of trial NCT03505723?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 9,535 participants. The study started on 2018-06-27. Estimated completion is 2023-02-03.
What interventions are being tested in trial NCT03505723?
The interventions under investigation include: Tranexamic Acid (DRUG), Placebo (Saline) (DRUG), Perioperative hypotension-avoidance strategy (OTHER), Perioperative hypertension-avoidance strategy (OTHER).
Who is sponsoring clinical trial NCT03505723?
This trial is sponsored by Population Health Research Institute, which has 21 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03505723's enrollment target sits among peer trials
9,535 30th of 2000 higher than 1,971 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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