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NCT03496181 · ClinicalTrials.gov registry record
Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently
A clinical trial, sponsored by Memorial Sloan Kettering Cancer Center.
- Completed
- Registry status
- 32
- Enrollment target
NCT03496181: Completed study, sponsored by Memorial Sloan Kettering Cancer Center.
NCT03496181 is a clinical trial that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 32 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03496181 has completed, sponsored by Memorial Sloan Kettering Cancer Center.
- COMPLETED
- Registry status
- 32 participants
- Enrollment target
Study Summary
Functional magnetic resonance imaging (fMRI) is a non-invasive test used to detect changes in brain activity by taking picture of changes in blood flow. The imaging helps doctors better understand how the brain works. Task based fMRI (TB fMRI) prompts patients to perform different activities (e.g. word selection in a reading task), and is routinely performed on patients in preparation for a Neurological surgery (surgery that involves the nervous system, brain and/or spinal cord). The purpose is to locate areas of the brain that control speech and movement; these images will help make decisions about patient surgeries. However, there are however gaps in knowledge specific to the language areas of the brain, especially for non-English patients and bilingual patients (those who are fluent in more than one language). This study proposes to evaluate if resting state fMRI (RS fMRI) that does not require any tasks, along with a novel way to analyze these images using "graphy theory," may provide more information. Graph theory is a new mathematical method to analyze the fMRI data. The overall goal is to determine if graph theory analysis on RS fMRI may reduce differences in health care treatment and outcomes for non-English speaking and bilingual patients. We hope that the results of this study will allow doctors to perform pre-operative fMRI in patients who do not speak English.
Interventions
- BEHAVIORAL Multilingual Aphasia Examination
- DIAGNOSTIC_TEST Language paradigms + RS fMRI
- DIAGNOSTIC_TEST Language paradigms + RS fMRI + one anatomical sequence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2018-03-30 |
| Est. Completion | 2025-05-08 |
What the finished NCT03496181 record still lists
NCT03496181 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 32 participants, a relatively small participant target.
The record links to 0 conditions, and to 3 interventions - of which Multilingual Aphasia Examination is the first listed.
NCT03496181 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03496181 about?
NCT03496181 is a clinical study titled "Evaluation of Functional Magnetic Resonance Imaging (fMRI) in Patients Who Speak Two Languages Fluently". Functional magnetic resonance imaging (fMRI) is a non-invasive test used to detect changes in brain activity by taking picture of changes in blood flow. The imaging helps doctors better understand how the brain works. Task based fMRI (TB fMRI) prompts patients to perform different activities (e.g. w...
What is the current status of trial NCT03496181?
This trial is currently completed. The enrollment target is 32 participants. The study started on 2018-03-30. Estimated completion is 2025-05-08.
What interventions are being tested in trial NCT03496181?
The interventions under investigation include: Multilingual Aphasia Examination (BEHAVIORAL), Language paradigms + RS fMRI (DIAGNOSTIC_TEST), Language paradigms + RS fMRI + one anatomical sequence (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03496181?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
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