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NCT03491150 · ClinicalTrials.gov registry record · Phase 3

An Open-Label Crenezumab Study in Participants With Alzheimer's Disease

A Phase 3 study, sponsored by Hoffmann-La Roche.

Terminated
Registry status
Phase 3
Development phase
149
Enrollment target

NCT03491150 is a Phase 3 study that was terminated before completion, run by Hoffmann-La Roche. The registered enrollment target is 149 participants.

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The verdict

NCT03491150, a Phase 3 study, was terminated before completion, sponsored by Hoffmann-La Roche.

TERMINATED
Registry status
Phase 3
Development phase
149 participants
Enrollment target

Study Summary

In the BN40031 OLE study, a dose of crenezumab of 60 mg/kg intravenous (IV) every 4 weeks (Q4W) will be offered to all participants who complete Study BN29552 or BN29553 and who meet eligibility criteria in order to evaluate safety in participants on long-term crenezumab treatment and to investigate the effect of crenezumab on the underlying disease process and disease course as an exploratory efficacy objective.

Interventions

  • DRUG Crenezumab

Trial Details

FieldValue
Enrollment Target 149 participants
Start Date 2018-04-11
Est. Completion 2019-05-31
Phase Phase 3

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT03491150

The ClinicalTrials.gov registry entry for NCT03491150 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 149 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Crenezumab is the first listed.

NCT03491150 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03491150 about?

NCT03491150 is a clinical study titled "An Open-Label Crenezumab Study in Participants With Alzheimer's Disease". In the BN40031 OLE study, a dose of crenezumab of 60 mg/kg intravenous (IV) every 4 weeks (Q4W) will be offered to all participants who complete Study BN29552 or BN29553 and who meet eligibility criteria in order to evaluate safety in participants on long-term crenezumab treatment and to investigate...

What is the current status of trial NCT03491150?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 149 participants. The study started on 2018-04-11. Estimated completion is 2019-05-31.

What interventions are being tested in trial NCT03491150?

The interventions under investigation include: Crenezumab (DRUG).

Who is sponsoring clinical trial NCT03491150?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.