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NCT03488550 · ClinicalTrials.gov registry record · Phase 1

Single-dose Study of ANX007 in Participants With Primary Open-angle Glaucoma

A Phase 1 study, sponsored by Annexon.

Completed
Registry status
Phase 1
Development phase
9
Enrollment target

NCT03488550: Completed Phase 1 study, sponsored by Annexon.

NCT03488550 is a Phase 1 study that has completed, run by Annexon. The registered enrollment target is 9 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03488550, a Phase 1 study, has completed, sponsored by Annexon.

COMPLETED
Registry status
Phase 1
Development phase
9 participants
Enrollment target

Study Summary

This is a multi center, open-label, single dose, safety study. Approximately 9 to 15 participants with open-angle glaucoma are assigned into 3 sequential dose-levels and will receive ANX007 administered as single, IVT injections.

Interventions

  • BIOLOGICAL ANX007

Trial Details

FieldValue
Enrollment Target 9 participants
Start Date 2018-03-23
Est. Completion 2018-08-03
Phase Phase 1
Annexon

8 total trials

What the finished NCT03488550 record still lists

NCT03488550 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (85% lower).

The record links to 0 conditions, and to 1 intervention - of which ANX007 is the first listed.

NCT03488550 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03488550 about?

NCT03488550 is a clinical study titled "Single-dose Study of ANX007 in Participants With Primary Open-angle Glaucoma". This is a multi center, open-label, single dose, safety study. Approximately 9 to 15 participants with open-angle glaucoma are assigned into 3 sequential dose-levels and will receive ANX007 administered as single, IVT injections.

What is the current status of trial NCT03488550?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2018-03-23. Estimated completion is 2018-08-03.

What interventions are being tested in trial NCT03488550?

The interventions under investigation include: ANX007 (BIOLOGICAL).

Who is sponsoring clinical trial NCT03488550?

This trial is sponsored by Annexon, which has 8 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03488550's enrollment target sits among peer trials

9 1955th of 2000 higher than 42 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03488550, the US trial registry maintained by the National Library of Medicine. NCT03488550 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.