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NCT03485924 · ClinicalTrials.gov registry record · NA
EUS FNB Versus FNA With On-Site Cytopathology in Solid Pancreatic Masses
A NA study, sponsored by Johns Hopkins University.
- Terminated
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT03485924: Clinical Trial NA study, sponsored by Johns Hopkins University.
NCT03485924 is a NA study that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03485924, a NA study, was terminated before completion, sponsored by Johns Hopkins University.
- TERMINATED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
The objective of this paired cohort study is to evaluate the diagnostic accuracy of Endoscopic Ultrasound-fine needle aspiration (EUS-FNA) with rapid onsite evaluation (ROSE) compared to EUS-fine needle biopsy (EUS-FNB) without ROSE. If EUS-FNB without ROSE is shown to be non-inferior to the current standard of care of EUS-FNA with ROSE in pancreatic lesions, this study has the potential to make EUS-guided tissue acquisition more economical (with elimination for the need for cytopathology staff onsite) as well as provide core histological specimen without sacrificing the overall diagnostic yield.
Primary Outcome
Diagnostic accuracy will be defined as (true positive + true negative)/all participants in the arm.
Interventions
- DIAGNOSTIC_TEST EUS-FNA with ROSE
- DIAGNOSTIC_TEST EUS-FNB without ROSE
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2018-04-12 |
| Est. Completion | 2023-07-26 |
| Phase | NA |
Why NCT03485924 stopped before completion
NCT03485924 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which EUS-FNA with ROSE is the first listed.
NCT03485924 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03485924 about?
NCT03485924 is a clinical study titled "EUS FNB Versus FNA With On-Site Cytopathology in Solid Pancreatic Masses". The objective of this paired cohort study is to evaluate the diagnostic accuracy of Endoscopic Ultrasound-fine needle aspiration (EUS-FNA) with rapid onsite evaluation (ROSE) compared to EUS-fine needle biopsy (EUS-FNB) without ROSE. If EUS-FNB without ROSE is shown to be non-inferior to the current...
What is the current status of trial NCT03485924?
This trial is currently terminated. It is a NA study. The enrollment target is 40 participants. The study started on 2018-04-12. Estimated completion is 2023-07-26.
What interventions are being tested in trial NCT03485924?
The interventions under investigation include: EUS-FNA with ROSE (DIAGNOSTIC_TEST), EUS-FNB without ROSE (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03485924?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03485924's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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