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NCT03481608 · ClinicalTrials.gov registry record · NA
The Effect of Dietary Lauric Acid on the Production of the LRH-1 Ligand, Dilauroylphosphatidylcholine
A NA study, sponsored by Cornell University.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT03481608: Completed NA study, sponsored by Cornell University.
NCT03481608 is a NA study that has completed, run by Cornell University. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03481608, a NA study, has completed, sponsored by Cornell University.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
A phosphatidylcholine species enriched with lauric acid at both the sn-1 and sn-2 positions, dilauroylphosphatidylcholine (DLPC), was recently identified as a ligand for the nuclear receptor, liver receptor homolog-1 (LRH-1). To date, DLPC has not been reported in vitro or in vivo, and has yet to be catalogued in the human metabolomics database. This intervention trial aims to determine the impact of consumption of dietary lauric acid, in the form of coconut oil (49% lauric acid), can facilitate the production of DLPC in humans.
Primary Outcome
The presence of DLPC in postprandial serum will be measured using Liquid Chromatography Tandem Mass Spectrometry
Interventions
- OTHER Lauric acid (coconut oil)
- OTHER No Lauric acid (olive oil)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2018-03-19 |
| Est. Completion | 2018-04-22 |
| Phase | NA |
What the finished NCT03481608 record still lists
NCT03481608 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Lauric acid (coconut oil) is the first listed.
NCT03481608 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03481608 about?
NCT03481608 is a clinical study titled "The Effect of Dietary Lauric Acid on the Production of the LRH-1 Ligand, Dilauroylphosphatidylcholine". A phosphatidylcholine species enriched with lauric acid at both the sn-1 and sn-2 positions, dilauroylphosphatidylcholine (DLPC), was recently identified as a ligand for the nuclear receptor, liver receptor homolog-1 (LRH-1). To date, DLPC has not been reported in vitro or in vivo, and has yet to be...
What is the current status of trial NCT03481608?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2018-03-19. Estimated completion is 2018-04-22.
What interventions are being tested in trial NCT03481608?
The interventions under investigation include: Lauric acid (coconut oil) (OTHER), No Lauric acid (olive oil) (OTHER).
Who is sponsoring clinical trial NCT03481608?
This trial is sponsored by Cornell University, which has 66 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03481608's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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