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NCT03468933 · ClinicalTrials.gov registry record · Phase 4
Fibrinolysis Compared to Thoracoscopy for Pleural Infection
A Phase 4 study, sponsored by Tulane University.
- Completed
- Registry status
- Phase 4
- Development phase
- 32
- Enrollment target
NCT03468933: Completed Phase 4 study, sponsored by Tulane University.
NCT03468933 is a Phase 4 study that has completed, run by Tulane University. The registered enrollment target is 32 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03468933, a Phase 4 study, has completed, sponsored by Tulane University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 32 participants
- Enrollment target
Study Summary
The purpose of this prospective randomized clinical trial is to compare two currently accepted standard-of-care treatment strategies: Medical thoracoscopy as compared to instillation of intrapleural tissue Plasminogen Activator (TPA) and human recombinant Deoxyribonuclease (DNase) for the management of empyema or complicated parapneumonic effusion (CPPE) in adults.
Primary Outcome
duration of hospital stay in days from time of procedure to discharge from hospital.
Interventions
- DRUG tissue plasminogen activator (tPA) and human recombinant deoxyribonuclease (DNase)
- PROCEDURE Medical Thoracoscopy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2017-11-01 |
| Est. Completion | 2019-12-30 |
| Phase | Phase 4 |
What the finished NCT03468933 record still lists
NCT03468933 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 2 interventions - of which tissue plasminogen activator (tPA) and human recombinant deoxyribonuclease (DNase) is the first listed.
NCT03468933 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03468933 about?
NCT03468933 is a clinical study titled "Fibrinolysis Compared to Thoracoscopy for Pleural Infection". The purpose of this prospective randomized clinical trial is to compare two currently accepted standard-of-care treatment strategies: Medical thoracoscopy as compared to instillation of intrapleural tissue Plasminogen Activator (TPA) and human recombinant Deoxyribonuclease (DNase) for the management...
What is the current status of trial NCT03468933?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 32 participants. The study started on 2017-11-01. Estimated completion is 2019-12-30.
What interventions are being tested in trial NCT03468933?
The interventions under investigation include: tissue plasminogen activator (tPA) and human recombinant deoxyribonuclease (DNase) (DRUG), Medical Thoracoscopy (PROCEDURE).
Who is sponsoring clinical trial NCT03468933?
This trial is sponsored by Tulane University, which has 73 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03468933's enrollment target sits among peer trials
32 1534th of 2000 higher than 457 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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