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NCT03461705 · ClinicalTrials.gov registry record · NA
Novel Adenosine-independent Index of Coronary Artery Stenosis Severity Resting Flow Reserve
A NA study, sponsored by Columbia University.
- Terminated
- Registry status
- NA
- Development phase
- 5
- Enrollment target
NCT03461705: Clinical Trial NA study, sponsored by Columbia University.
NCT03461705 is a NA study that was terminated before completion, run by Columbia University. The registered enrollment target is 5 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03461705, a NA study, was terminated before completion, sponsored by Columbia University.
- TERMINATED
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
Study Summary
This study will enroll patients who are referred for coronary angiography and require physiological assessment to see if the lesion can be treated as per the local standard of care. Approximately 92 participants will be enrolled. There are no follow up visits required so participation in this study will end when subjects are discharged from the hospital.The study will be comparing the resting flow reserve against the instantaneous wave-free ratio (iFR) and fractional flow reserve. All these tests offer a way to image a legion and determine if it is suitable to be treated. FFR measures the pressure differences across (narrowed coronary arteries usually due to atherosclerosis), iFR's are performed during cardiac catheterisation (angiography) using invasive coronary pressure wires which are placed in the arteries of the heart that are to be assessed and the Resting flow reserve looks at the maximum increase in blood flow through the coronary arteries above the normal resting volume.
Primary Outcome
Mean RFR measurements will be compared against mean iFR measurements to determine if there is an agreement between RFR and iFR for detection of ischemia.
Interventions
- DEVICE Volcano Verrata Pressure Wire
- DEVICE St. Jude Medical (SJM) Aeris Pressure Wire System
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2017-10-20 |
| Est. Completion | 2018-08-02 |
| Phase | NA |
Why NCT03461705 stopped before completion
NCT03461705 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Volcano Verrata Pressure Wire is the first listed.
NCT03461705 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03461705 about?
NCT03461705 is a clinical study titled "Novel Adenosine-independent Index of Coronary Artery Stenosis Severity Resting Flow Reserve". This study will enroll patients who are referred for coronary angiography and require physiological assessment to see if the lesion can be treated as per the local standard of care. Approximately 92 participants will be enrolled. There are no follow up visits required so participation in this study ...
What is the current status of trial NCT03461705?
This trial is currently terminated. It is a NA study. The enrollment target is 5 participants. The study started on 2017-10-20. Estimated completion is 2018-08-02.
What interventions are being tested in trial NCT03461705?
The interventions under investigation include: Volcano Verrata Pressure Wire (DEVICE), St. Jude Medical (SJM) Aeris Pressure Wire System (DEVICE).
Who is sponsoring clinical trial NCT03461705?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03461705's enrollment target sits among peer trials
5 1988th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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