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NCT03460990 · ClinicalTrials.gov registry record · Phase 3
A Study of VX-659 Combination Therapy in CF Subjects Homozygous for F508del (F/F)
A Phase 3 study, sponsored by Vertex Pharmaceuticals Incorporated.
- Completed
- Registry status
- Phase 3
- Development phase
- 116
- Enrollment target
NCT03460990 is a Phase 3 study that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 116 participants.
The verdict
NCT03460990, a Phase 3 study, has completed, sponsored by Vertex Pharmaceuticals Incorporated.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 116 participants
- Enrollment target
Study Summary
This study will evaluate the efficacy of VX-659 in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects with cystic fibrosis (CF) who are homozygous for the F508del mutation (F/F).
Interventions
- DRUG Placebo
- DRUG IVA
- DRUG TEZ/IVA
- DRUG VX-659/TEZ/IVA
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 116 participants |
| Start Date | 2018-05-01 |
| Est. Completion | 2018-10-08 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03460990
The ClinicalTrials.gov registry entry for NCT03460990 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 116 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vertex Pharmaceuticals Incorporated, which has 191 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.
NCT03460990 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03460990 about?
NCT03460990 is a clinical study titled "A Study of VX-659 Combination Therapy in CF Subjects Homozygous for F508del (F/F)". This study will evaluate the efficacy of VX-659 in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects with cystic fibrosis (CF) who are homozygous for the F508del mutation (F/F).
What is the current status of trial NCT03460990?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 116 participants. The study started on 2018-05-01. Estimated completion is 2018-10-08.
What interventions are being tested in trial NCT03460990?
The interventions under investigation include: Placebo (DRUG), IVA (DRUG), TEZ/IVA (DRUG), VX-659/TEZ/IVA (DRUG).
Who is sponsoring clinical trial NCT03460990?
This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.
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