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NCT03459222 · ClinicalTrials.gov registry record · Phase 1

An Investigational Study of Immunotherapy Combinations in Participants With Solid Cancers That Are Advanced or Have Spread

A Phase 1 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 1
Development phase
229
Enrollment target

NCT03459222 is a Phase 1 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 229 participants.

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The verdict

NCT03459222, a Phase 1 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 1
Development phase
229 participants
Enrollment target

Study Summary

The purpose of this study is to demonstrate the safety and preliminary activity with triple combinations of relatlimab in combination with nivolumab and BMS-986205, or in combination with nivolumab and ipilimumab in immunotherapy-naive and pretreated populations across select advanced tumor types.

Interventions

  • BIOLOGICAL Nivolumab
  • BIOLOGICAL Ipilimumab
  • BIOLOGICAL Relatlimab
  • DRUG BMS-986205

Trial Details

FieldValue
Enrollment Target 229 participants
Start Date 2018-05-30
Est. Completion 2025-02-19
Phase Phase 1

Sponsor

Bristol-Myers Squibb

1,025 total trials

What the Registry Record Tells You About NCT03459222

The ClinicalTrials.gov registry entry for NCT03459222 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 229 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bristol-Myers Squibb, which has 1,025 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Nivolumab is the first listed.

NCT03459222 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03459222 about?

NCT03459222 is a clinical study titled "An Investigational Study of Immunotherapy Combinations in Participants With Solid Cancers That Are Advanced or Have Spread". The purpose of this study is to demonstrate the safety and preliminary activity with triple combinations of relatlimab in combination with nivolumab and BMS-986205, or in combination with nivolumab and ipilimumab in immunotherapy-naive and pretreated populations across select advanced tumor types.

What is the current status of trial NCT03459222?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 229 participants. The study started on 2018-05-30. Estimated completion is 2025-02-19.

What interventions are being tested in trial NCT03459222?

The interventions under investigation include: Nivolumab (BIOLOGICAL), Ipilimumab (BIOLOGICAL), Relatlimab (BIOLOGICAL), BMS-986205 (DRUG).

Who is sponsoring clinical trial NCT03459222?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.