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NCT03458780 · ClinicalTrials.gov registry record

Yellow Fever Immune Response at Single Cell Resolution

A clinical trial, sponsored by Rockefeller University.

Completed
Registry status
6
Enrollment target

NCT03458780: Completed study, sponsored by Rockefeller University.

NCT03458780 is a clinical trial that has completed, run by Rockefeller University. The registered enrollment target is 6 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03458780 has completed, sponsored by Rockefeller University.

COMPLETED
Registry status
6 participants
Enrollment target

Study Summary

The immune system is composed of diverse cell types with different functions that act together in order to defend against infection. This pilot study will test a new technology for studying these many different cell types at very large numbers at the level of individual cells. This method will then be used to identify the cell types and functions important for the immune response to the highly protective yellow fever vaccine, which will improve our understanding of effective vaccine features.

Primary Outcome

The feasibility and accuracy of inDrop RNA-Seq for distinguishing different cell types will be assessed by comparing (for concordance) cell subset population frequency and distribution values determined by inDrop RNA-seq to cell subset population frequency and distribution values determined by flow cytometry immunophenotyping, the present "gold standard" technique.

Interventions

  • DRUG Yellow Fever Vaccine

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2016-08-22
Est. Completion 2018-09-05
Rockefeller University

117 total trials

What the finished NCT03458780 record still lists

NCT03458780 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 6 participants, a relatively small participant target.

The record links to 0 conditions, and to 1 intervention - of which Yellow Fever Vaccine is the first listed.

NCT03458780 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03458780 about?

NCT03458780 is a clinical study titled "Yellow Fever Immune Response at Single Cell Resolution". The immune system is composed of diverse cell types with different functions that act together in order to defend against infection. This pilot study will test a new technology for studying these many different cell types at very large numbers at the level of individual cells. This method will then ...

What is the current status of trial NCT03458780?

This trial is currently completed. The enrollment target is 6 participants. The study started on 2016-08-22. Estimated completion is 2018-09-05.

What interventions are being tested in trial NCT03458780?

The interventions under investigation include: Yellow Fever Vaccine (DRUG).

Who is sponsoring clinical trial NCT03458780?

This trial is sponsored by Rockefeller University, which has 117 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT03458780, the US trial registry maintained by the National Library of Medicine. NCT03458780 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.