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NCT03454087 · ClinicalTrials.gov registry record · NA
Study of Early Enteral Dextrose in Sepsis
A NA study, sponsored by University of Pittsburgh.
- Completed
- Registry status
- NA
- Development phase
- 58
- Enrollment target
NCT03454087 is a NA study that has completed, run by University of Pittsburgh. The registered enrollment target is 58 participants.
The verdict
NCT03454087, a NA study, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- NA
- Development phase
- 58 participants
- Enrollment target
Study Summary
This study is a prospective single-center randomized double-blinded placebo-controlled clinical trial testing the effects of early enteral dextrose as a therapeutic agent in critically ill patients with sepsis. Primary outcomes are differences in circulating plasma levels of the pro-inflammatory cytokine IL-6 to be tested 24 hours after the start of enteral infusion. Secondary outcomes include differences in circulating incretin hormone levels, differences in other pro-inflammatory cytokines including IL-1β and TNF-α, changes in intestinal microbial composition and function after intervention, glycemic control and variability as assessed by capillary blood glucose measurements and exogenous insulin dosing during the intervention period, and clinical outcomes including intensive care unit (ICU) and hospital stay and in-hospital mortality.
Interventions
- OTHER Enteral Dextrose Infusion
- OTHER Free Water Infusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 58 participants |
| Start Date | 2018-06-04 |
| Est. Completion | 2020-04-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03454087
The ClinicalTrials.gov registry entry for NCT03454087 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 58 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Enteral Dextrose Infusion is the first listed.
NCT03454087 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03454087 about?
NCT03454087 is a clinical study titled "Study of Early Enteral Dextrose in Sepsis". This study is a prospective single-center randomized double-blinded placebo-controlled clinical trial testing the effects of early enteral dextrose as a therapeutic agent in critically ill patients with sepsis. Primary outcomes are differences in circulating plasma levels of the pro-inflammatory cyt...
What is the current status of trial NCT03454087?
This trial is currently completed. It is a NA study. The enrollment target is 58 participants. The study started on 2018-06-04. Estimated completion is 2020-04-01.
What interventions are being tested in trial NCT03454087?
The interventions under investigation include: Enteral Dextrose Infusion (OTHER), Free Water Infusion (OTHER).
Who is sponsoring clinical trial NCT03454087?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
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