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NCT03451071 · ClinicalTrials.gov registry record · Phase 4

Postpartum HPV Vaccination

A Phase 4 study, sponsored by University of Alabama at Birmingham.

Completed
Registry status
Phase 4
Development phase
195
Enrollment target

NCT03451071: Completed Phase 4 study, sponsored by University of Alabama at Birmingham.

NCT03451071 is a Phase 4 study that has completed, run by University of Alabama at Birmingham. The registered enrollment target is 195 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03451071, a Phase 4 study, has completed, sponsored by University of Alabama at Birmingham.

COMPLETED
Registry status
Phase 4
Development phase
195 participants
Enrollment target

Study Summary

Human papillomavirus (HPV)-related cancers are on the rise in the United States. Furthermore, greater than 90% of cervical cancer cases are attributable to HPV, and cervical cancer disproportionately affects women of color in both incidence and mortality. Due to low HPV vaccine uptake in the US, innovative approaches to vaccinating vulnerable populations are necessary in order to maximize the cancer prevention potential of this vaccine. The puerperium is a time period when women are engaged in the healthcare system and have almost universal access to affordable health care. Two prior studies have shown that postpartum HPV vaccination is acceptable to patients, and high rates of vaccination were achieved in these primarily Hispanic populations. However, data show that the immune response in young women is less robust than in adolescents, and no studies have examined immunogenicity in postpartum women specifically. We propose an HPV vaccination pilot study in women who receive postpartum care at University of Alabama at Birmingham (UAB) hospital. We will examine the acceptability, uptake and immunogenicity of the vaccine in the postpartum setting.

Primary Outcome

This was established using a survey to indicate willingness to receive vaccine.

Interventions

  • DRUG Gardasil9

Trial Details

FieldValue
Enrollment Target 195 participants
Start Date 2019-04-29
Est. Completion 2020-12-30
Phase Phase 4
University of Alabama at Birmingham

1,160 total trials

What the finished NCT03451071 record still lists

NCT03451071 is an interventional study that assigns participants to a tested intervention. The registered 195 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (62% lower).

The record links to 0 conditions, and to 1 intervention - of which Gardasil9 is the first listed.

NCT03451071 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03451071 about?

NCT03451071 is a clinical study titled "Postpartum HPV Vaccination". Human papillomavirus (HPV)-related cancers are on the rise in the United States. Furthermore, greater than 90% of cervical cancer cases are attributable to HPV, and cervical cancer disproportionately affects women of color in both incidence and mortality. Due to low HPV vaccine uptake in the US, inn...

What is the current status of trial NCT03451071?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 195 participants. The study started on 2019-04-29. Estimated completion is 2020-12-30.

What interventions are being tested in trial NCT03451071?

The interventions under investigation include: Gardasil9 (DRUG).

Who is sponsoring clinical trial NCT03451071?

This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03451071's enrollment target sits among peer trials

195 450th of 2000 higher than 1,550 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03451071, the US trial registry maintained by the National Library of Medicine. NCT03451071 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.