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NCT03447990 · ClinicalTrials.gov registry record · Phase 1
v4 Study Evaluating the Safety, Tolerability and Preliminary Pharmacokinetics and Pharmacodynamics of MYK-491
A Phase 1 study, sponsored by Bristol-Myers Squibb.
- Completed
- Registry status
- Phase 1
- Development phase
- 52
- Enrollment target
NCT03447990: Completed Phase 1 study, sponsored by Bristol-Myers Squibb.
NCT03447990 is a Phase 1 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 52 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (13% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03447990, a Phase 1 study, has completed, sponsored by Bristol-Myers Squibb.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 52 participants
- Enrollment target
Study Summary
The purpose of this Phase 1b/2a study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of MYK-491 in patients with stable heart failure.
Primary Outcome
Number of participants with any grade of treatment-emergent adverse events (TEAEs) and any grade of serious adverse events (SAEs).
Interventions
- DRUG Placebo
- DRUG MYK-491
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2018-02-06 |
| Est. Completion | 2019-10-24 |
| Phase | Phase 1 |
What the finished NCT03447990 record still lists
NCT03447990 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 52 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (13% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT03447990 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03447990 about?
NCT03447990 is a clinical study titled "v4 Study Evaluating the Safety, Tolerability and Preliminary Pharmacokinetics and Pharmacodynamics of MYK-491". The purpose of this Phase 1b/2a study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of MYK-491 in patients with stable heart failure.
What is the current status of trial NCT03447990?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 52 participants. The study started on 2018-02-06. Estimated completion is 2019-10-24.
What interventions are being tested in trial NCT03447990?
The interventions under investigation include: Placebo (DRUG), MYK-491 (DRUG).
Who is sponsoring clinical trial NCT03447990?
This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03447990's enrollment target sits among peer trials
52 956th of 2000 higher than 1,032 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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