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NCT03444714 · ClinicalTrials.gov registry record · Phase 1
Phase I Study of RiMO-301 With Radiation in Advanced Tumors
A Phase 1 study, sponsored by Coordination Pharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 32
- Enrollment target
NCT03444714: Completed Phase 1 study, sponsored by Coordination Pharmaceuticals.
NCT03444714 is a Phase 1 study that has completed, run by Coordination Pharmaceuticals. The registered enrollment target is 32 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03444714, a Phase 1 study, has completed, sponsored by Coordination Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 32 participants
- Enrollment target
Study Summary
This is a prospective, open-label, single arm, non-randomized study of RiMO-301 with radiation in patients with advanced tumors. A single escalation dose of RiMO-301 is intratumorally injected in a 3 + 3 study design to identify the recommended dose and dosing volumes. Condition or Disease: Patient with advanced tumor which is clinically accessible for intratumoral injection Intervention/Treatment: Drug - RiMO-301 Radiation - Radiotherapy Phase: Phase 1
Primary Outcome
• To determine the maximum tolerated dose (MTD), which is defined as the dose level at which fewer than 33% of patients experience a dose limiting toxicity (DLT) using a 3+3 strategy
Interventions
- DRUG RiMO-301
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2018-04-10 |
| Est. Completion | 2025-06-16 |
| Phase | Phase 1 |
What the finished NCT03444714 record still lists
NCT03444714 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower).
The record links to 0 conditions, and to 1 intervention - of which RiMO-301 is the first listed.
NCT03444714 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03444714 about?
NCT03444714 is a clinical study titled "Phase I Study of RiMO-301 With Radiation in Advanced Tumors". This is a prospective, open-label, single arm, non-randomized study of RiMO-301 with radiation in patients with advanced tumors. A single escalation dose of RiMO-301 is intratumorally injected in a 3 + 3 study design to identify the recommended dose and dosing volumes. Condition or Disease: Patien...
What is the current status of trial NCT03444714?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2018-04-10. Estimated completion is 2025-06-16.
What interventions are being tested in trial NCT03444714?
The interventions under investigation include: RiMO-301 (DRUG).
Who is sponsoring clinical trial NCT03444714?
This trial is sponsored by Coordination Pharmaceuticals, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03444714's enrollment target sits among peer trials
32 1296th of 2000 higher than 679 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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