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NCT03443180 · ClinicalTrials.gov registry record · NA
Gluten and Amylase Trypsin Inhibitors (ATI) Free Diet
A NA study, sponsored by Medical College of Wisconsin.
- Completed
- Registry status
- NA
- Development phase
- 32
- Enrollment target
NCT03443180: Completed NA study, sponsored by Medical College of Wisconsin.
NCT03443180 is a NA study that has completed, run by Medical College of Wisconsin. The registered enrollment target is 32 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03443180, a NA study, has completed, sponsored by Medical College of Wisconsin.
- COMPLETED
- Registry status
- NA
- Development phase
- 32 participants
- Enrollment target
Study Summary
Siblings of those with type 1 diabetes are at an increased risk of developing the disease themselves. Through prior research, the investigators have found that siblings as well as those with type 1 diabetes have a general level of inflammation in the body. The investigators are examining the role that diet plays in this level of inflammation by asking siblings of children with type 1 diabetes to go on a gluten and Amylase Trypsin Inhibitors (ATI)-free diet for 4 weeks. Blood and stool samples will be measured before the diet, after the diet is completed and again 4 weeks after participants resume their normal diet.
Primary Outcome
Investigators will measure the participants overall immune inflammation and regulation by a plasma-induced transcriptional bioassay. The change in this bioassay will be determined for each subject and the entire group both before and after the dietary intervention. This bioassay informs the investigators of which genes may be positively or negatively impacted by this dietary change and whether the removal of gluten and amylase trypsin inhibitors (ATI) affects a participant's immune state.
Interventions
- OTHER Gluten and Amylase Trypsin Inhibitors (ATI)-free diet
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2018-01-01 |
| Est. Completion | 2020-03-09 |
| Phase | NA |
What the finished NCT03443180 record still lists
NCT03443180 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Gluten and Amylase Trypsin Inhibitors (ATI)-free diet is the first listed.
NCT03443180 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03443180 about?
NCT03443180 is a clinical study titled "Gluten and Amylase Trypsin Inhibitors (ATI) Free Diet". Siblings of those with type 1 diabetes are at an increased risk of developing the disease themselves. Through prior research, the investigators have found that siblings as well as those with type 1 diabetes have a general level of inflammation in the body. The investigators are examining the role th...
What is the current status of trial NCT03443180?
This trial is currently completed. It is a NA study. The enrollment target is 32 participants. The study started on 2018-01-01. Estimated completion is 2020-03-09.
What interventions are being tested in trial NCT03443180?
The interventions under investigation include: Gluten and Amylase Trypsin Inhibitors (ATI)-free diet (OTHER).
Who is sponsoring clinical trial NCT03443180?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03443180's enrollment target sits among peer trials
32 1578th of 2000 higher than 409 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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