Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03442465 · ClinicalTrials.gov registry record
Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas
A clinical trial of Osteosarcoma and Chondrosarcoma, sponsored by Memorial Sloan Kettering Cancer Center.
- Recruiting
- Registry status
- 300
- Enrollment target
- 3
- Study locations
NCT03442465: Recruiting study of Osteosarcoma and Chondrosarcoma, sponsored by Memorial Sloan Kettering Cancer Center.
NCT03442465 is a study of Osteosarcoma and Chondrosarcoma that is actively recruiting participants, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 300 participants, roughly in line with the 295-participant average among 46 other Osteosarcoma trials with a reported enrollment target. The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03442465, a study of Osteosarcoma and Chondrosarcoma, is actively recruiting participants, sponsored by Memorial Sloan Kettering Cancer Center.
- RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purpose of this study is to look at the amount of function that returns in participants that have reconstruction with bone graft or artificial device and in participants who have tumor surgery plus regenerative osseous surgery. The study will look at the level of function for a period of 3 years after the surgery. Another purpose of this study is to look at how well the bone heals in participants undergoing regenerative surgery
Primary Outcome
The primary objective is to assess early recovery level of function of all participants undergoing reconstructive surgery after resection of osseous neoplasms. The early time frame is considered at one year from the neoplasm resection surgery.
Conditions Studied
Interventions
- BEHAVIORAL Timed Get Up and Go Test
- BEHAVIORAL Toronto Extremity Salvage Score
- BEHAVIORAL Musculoskeletal Tumor Society Score
- DIAGNOSTIC_TEST Orthogonal Radiographs
- DIAGNOSTIC_TEST Weight Bearing for lower extremities only
Study Locations (3)
New York
- Memorial Sloan Kettering Westchester (Consent and Followup) - Harrison
- Memorial Sloan Kettering Cancer Center - New York
New Jersey
- Memorial Sloan Kettering Monmouth (Consent and Followup) - Middletown
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2018-02-14 |
| Est. Completion | 2027-02-14 |
What NCT03442465 shows while recruiting
NCT03442465 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 295-participant average among 46 other Osteosarcoma trials with a reported enrollment target.
The record links to 6 conditions, with Osteosarcoma appearing as the primary indexed condition, and to 5 interventions - of which Timed Get Up and Go Test is the first listed.
NCT03442465 reports a single indexed study location in New York, New Jersey.
Frequently Asked Questions
What is clinical trial NCT03442465 about?
NCT03442465 is a clinical study titled "Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas". The purpose of this study is to look at the amount of function that returns in participants that have reconstruction with bone graft or artificial device and in participants who have tumor surgery plus regenerative osseous surgery. The study will look at the level of function for a period of 3 year...
What is the current status of trial NCT03442465?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2018-02-14. Estimated completion is 2027-02-14.
What conditions does trial NCT03442465 study?
This clinical trial studies the following conditions: Osteosarcoma, Chondrosarcoma, Bone Sarcoma, Ewing's Sarcoma, Osseous Sarcoma.
What interventions are being tested in trial NCT03442465?
The interventions under investigation include: Timed Get Up and Go Test (BEHAVIORAL), Toronto Extremity Salvage Score (BEHAVIORAL), Musculoskeletal Tumor Society Score (BEHAVIORAL), Orthogonal Radiographs (DIAGNOSTIC_TEST), Weight Bearing for lower extremities only (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03442465?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03442465 being conducted?
This trial has 3 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteosarcoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03442465's enrollment target sits among peer trials
300 4th of 46 higher than 43 of 46 other Osteosarcoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteosarcoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors
RECRUITING · Phase 1
-
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
RECRUITING · Phase 1
-
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors
RECRUITING · Phase 1
-
Losartan + Sunitinib in Treatment of Osteosarcoma
RECRUITING · Phase 1
-
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
RECRUITING · Phase 3
-
Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors
RECRUITING · Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00353483 · 300 participants
Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells
- NCT00588185 · 300 participants · NA
[18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer
- NCT00682032 · 300 participants · NA
The Effect of Beta-glucan in Non-Small Cell Lung Cancer
- NCT00870064 · 300 participants · NA
The Treatment of Type I Open Fractures in Pediatrics
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI