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NCT03440918 · ClinicalTrials.gov registry record · NA
Impact of a Procalcitonin Testing and Treatment Algorithm on Antibiotic Use and Outcomes in the Pediatric Intensive Care Unit
A NA study, sponsored by Vanderbilt University Medical Center.
- Completed
- Registry status
- NA
- Development phase
- 271
- Enrollment target
NCT03440918 is a NA study that has completed, run by Vanderbilt University Medical Center. The registered enrollment target is 271 participants.
The verdict
NCT03440918, a NA study, has completed, sponsored by Vanderbilt University Medical Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 271 participants
- Enrollment target
Study Summary
The timely use of antibiotics can reduce morbidity and mortality associated with bacterial infections, particularly in the intensive care unit setting (ICU). Long courses of antibiotics, however, are associated with the emergence of multi-drug resistant organisms and antibiotic-associated adverse events, such as C. difficile infections. Thus, antibiotic de-escalation is an important goal of antimicrobial stewardship programs. Procalcitonin (PCT) has been investigated as a biomarker for critically ill adult patients with bacterial infection, particularly pneumonia and sepsis. The proposed project will evaluate whether a PCT testing and treatment algorithm, implemented through daily antimicrobial stewardship audit and feedback, can promote early and safe antibiotic de-escalation in the pediatric ICU.
Interventions
- OTHER Procalcitonin-Guided Antimicrobial Stewardship
- OTHER Baseline Antimicrobial Stewardship
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 271 participants |
| Start Date | 2018-02-12 |
| Est. Completion | 2019-05-11 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03440918
The ClinicalTrials.gov registry entry for NCT03440918 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 271 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Procalcitonin-Guided Antimicrobial Stewardship is the first listed.
NCT03440918 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03440918 about?
NCT03440918 is a clinical study titled "Impact of a Procalcitonin Testing and Treatment Algorithm on Antibiotic Use and Outcomes in the Pediatric Intensive Care Unit". The timely use of antibiotics can reduce morbidity and mortality associated with bacterial infections, particularly in the intensive care unit setting (ICU). Long courses of antibiotics, however, are associated with the emergence of multi-drug resistant organisms and antibiotic-associated adverse ev...
What is the current status of trial NCT03440918?
This trial is currently completed. It is a NA study. The enrollment target is 271 participants. The study started on 2018-02-12. Estimated completion is 2019-05-11.
What interventions are being tested in trial NCT03440918?
The interventions under investigation include: Procalcitonin-Guided Antimicrobial Stewardship (OTHER), Baseline Antimicrobial Stewardship (OTHER).
Who is sponsoring clinical trial NCT03440918?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
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