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NCT03431610 · ClinicalTrials.gov registry record · Phase 1
A Phase 1b Study Assessing the PK, PD, Safety & Tolerability of SB414 in Atopic Dermatitis
A Phase 1 study, sponsored by Novan.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
NCT03431610: Completed Phase 1 study, sponsored by Novan.
NCT03431610 is a Phase 1 study that has completed, run by Novan. The registered enrollment target is 48 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03431610, a Phase 1 study, has completed, sponsored by Novan.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
Study Summary
This is a Phase 1b, 2-week study assessing the pharmacokinetics, pharmacodynamics, safety and tolerability of SB414 in subjects with mild to moderate AD.
Primary Outcome
Peak plasma concentrations of hMAP3 after topical application of SB414
Interventions
- DRUG Vehicle
- DRUG SB414 2%
- DRUG SB414 6%
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2017-11-13 |
| Est. Completion | 2018-05-11 |
| Phase | Phase 1 |
What the finished NCT03431610 record still lists
NCT03431610 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower).
The record links to 0 conditions, and to 3 interventions - of which Vehicle is the first listed.
NCT03431610 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03431610 about?
NCT03431610 is a clinical study titled "A Phase 1b Study Assessing the PK, PD, Safety & Tolerability of SB414 in Atopic Dermatitis". This is a Phase 1b, 2-week study assessing the pharmacokinetics, pharmacodynamics, safety and tolerability of SB414 in subjects with mild to moderate AD.
What is the current status of trial NCT03431610?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2017-11-13. Estimated completion is 2018-05-11.
What interventions are being tested in trial NCT03431610?
The interventions under investigation include: Vehicle (DRUG), SB414 2% (DRUG), SB414 6% (DRUG).
Who is sponsoring clinical trial NCT03431610?
This trial is sponsored by Novan, which has 18 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03431610's enrollment target sits among peer trials
48 1025th of 2000 higher than 948 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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