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NCT03424915 · ClinicalTrials.gov registry record
Exercise, Fitness and Tumor Profiling in Breast Cancer Patients
A clinical trial of Breast Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
- Active
- Registry status
- 42
- Enrollment target
- 7
- Study locations
NCT03424915: Active study of Breast Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
NCT03424915 is a study of Breast Cancer that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 42 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 7 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03424915, a study of Breast Cancer, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- 42 participants
- Enrollment target
- 7
- Study locations
Study Summary
This study is designed to find out how engaging in regular exercise (or not) alters the biology of breast tumors as well as the normal tissue (if available) surrounding the tumor. The investigators hope that findings from this initial study will guide the design of future studies to examine how changes in exercise alter breast tumor biology.
Primary Outcome
Eight-μm-thick representative sections of the fresh-frozen sample will be microdissected with a needle under a stereomicroscope (Olympus SZ61), to ensure \>70% of tumor cell content as previously described.(36) Matched germline DNA will be microdissected from adjacent normal breast tissue (if available) for each case; to avoid the possibility of morphologically appearing non-neoplastic cells harboring somatic mutations; we will prioritize the microdissection of stromal cells and avoid normal bre
Conditions Studied
Interventions
- OTHER Blood draw
- BEHAVIORAL Harvard Health Professionals survey
- OTHER CPET Procedures
- OTHER stool sample
- PROCEDURE Research Tissue sampling
Study Locations (7)
New York
- Memorial Sloan Kettering Commack (Consent and Follow-up) - Commack
- Memorial Sloan Kettering Westchester (Consent and Follow-up) - Harrison
- Memorial Sloan Kettering Cancer Center (Consent and Follow-up) - New York
- Memorial Sloan Kettering Nassau (Consent and Follow-up) - Uniondale
New Jersey
- Memorial Sloan Kettering Basking Ridge (Consent and Follow-up) - Basking Ridge
- Memorial Sloan Kettering Monmouth (Consent and Follow-up) - Middletown
- Memorial Sloan Kettering Bergen (Consent and Follow-up) - Montvale
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2018-01-31 |
| Est. Completion | 2027-01 |
What the registry record for NCT03424915 still lists
NCT03424915 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 5 interventions - of which Blood draw is the first listed.
NCT03424915 lists 7 locations in 2 states (New York, New Jersey).
Frequently Asked Questions
What is clinical trial NCT03424915 about?
NCT03424915 is a clinical study titled "Exercise, Fitness and Tumor Profiling in Breast Cancer Patients". This study is designed to find out how engaging in regular exercise (or not) alters the biology of breast tumors as well as the normal tissue (if available) surrounding the tumor. The investigators hope that findings from this initial study will guide the design of future studies to examine how chan...
What is the current status of trial NCT03424915?
This trial is currently active not recruiting. The enrollment target is 42 participants. The study started on 2018-01-31. Estimated completion is 2027-01.
What conditions does trial NCT03424915 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT03424915?
The interventions under investigation include: Blood draw (OTHER), Harvard Health Professionals survey (BEHAVIORAL), CPET Procedures (OTHER), stool sample (OTHER), Research Tissue sampling (PROCEDURE).
Who is sponsoring clinical trial NCT03424915?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03424915 being conducted?
This trial has 7 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03424915's enrollment target sits among peer trials
42 864th of 1224 higher than 356 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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