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NCT03424200 · ClinicalTrials.gov registry record · NA
Coaching for Cognition in Alzheimer's (COCOA)
A NA study, sponsored by Hoag Memorial Hospital Presbyterian.
- Completed
- Registry status
- NA
- Development phase
- 54
- Enrollment target
NCT03424200: Completed NA study, sponsored by Hoag Memorial Hospital Presbyterian.
NCT03424200 is a NA study that has completed, run by Hoag Memorial Hospital Presbyterian. The registered enrollment target is 54 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03424200, a NA study, has completed, sponsored by Hoag Memorial Hospital Presbyterian.
- COMPLETED
- Registry status
- NA
- Development phase
- 54 participants
- Enrollment target
Study Summary
One major study objective is, using 2 study arms (data-driven health coaching plus RC vs. RC only), to evaluate the efficacy of data-driven health coaching. 'RC only' will serve as the control group. Participants will be enrolled in the trial on the basis of an existence of objective cognitive impairment defined by the MCI Screen (MCIS) and being in one of three functional stages as defined by the Functional Assessment Staging Test (FAST). The three FAST stages correspond to cognitive impairment without functional impairment (FAST 2), cognitive impairment with functional impairment without impairment in instrumental activities of daily living (FAST 3, also known as mild cognitive impairment, MCI), or cognitive impairment with impaired instrumental activities of daily living (FAST 4). Study objectives include measuring treatment related changes in cognitive and functional abilities, quality of life, and biological or biochemical measures. A second major study objective is to analyze longitudinal multi-omic data from individuals on a trajectory of early-stage dementia, to discover correlations between measured variables, and identify models of causation that can further advance knowledge and research in brain degeneration and healthy living
Primary Outcome
Test the hypothesis that coaching is better than no coaching for people in the early stages and at risk for cognitive decline. We plan to test that after two years of coaching, participants in the coaching arm will have higher cognitive scores as measured by the MCI score. Participants in COCOA will be assessed with the MCIS, which quantifies cognition with the Memory Performance Index (MPI) component score on a 0 to 100 scale (below normal: \<50). The MPI will be our primary outcome measure fo
Interventions
- BEHAVIORAL Routine care
- OTHER Coaching plus routine care
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2018-01-10 |
| Est. Completion | 2022-01-01 |
| Phase | NA |
What the finished NCT03424200 record still lists
NCT03424200 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 54 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 2 interventions - of which Routine care is the first listed.
NCT03424200 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03424200 about?
NCT03424200 is a clinical study titled "Coaching for Cognition in Alzheimer's (COCOA)". One major study objective is, using 2 study arms (data-driven health coaching plus RC vs. RC only), to evaluate the efficacy of data-driven health coaching. 'RC only' will serve as the control group. Participants will be enrolled in the trial on the basis of an existence of objective cognitive impai...
What is the current status of trial NCT03424200?
This trial is currently completed. It is a NA study. The enrollment target is 54 participants. The study started on 2018-01-10. Estimated completion is 2022-01-01.
What interventions are being tested in trial NCT03424200?
The interventions under investigation include: Routine care (BEHAVIORAL), Coaching plus routine care (OTHER).
Who is sponsoring clinical trial NCT03424200?
This trial is sponsored by Hoag Memorial Hospital Presbyterian, which has 20 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03424200's enrollment target sits among peer trials
54 1268th of 2000 higher than 730 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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