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NCT03423589 · ClinicalTrials.gov registry record · NA
Modulation of Type 1 Diabetes Susceptibility Through the Use of Probiotics
A NA study, sponsored by Medical College of Wisconsin.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
NCT03423589 is a NA study that has completed, run by Medical College of Wisconsin. The registered enrollment target is 30 participants.
The verdict
NCT03423589, a NA study, has completed, sponsored by Medical College of Wisconsin.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
Study Summary
Investigators aim to further the understanding of environmental factors that underlie the progression to Type 1 diabetes (T1D). Dysbiosis, defined as alterations in intestinal microbiota composition and function, has been hypothesized to increase the risk of developing T1D in those with genetic susceptibility. Dysbiosis may result from modern dietary habits, such as broad consumption of the highly processed Western Diet, or by widespread use of antibiotics. Here, investigators propose to examine the impact of dysbiosis on the endogenous innate inflammation known to exist within families affected by T1D and if probiotic supplementation may beneficially modulate this inflammatory state. Participants will be asked to take the probiotic VSL#3 daily for six weeks. Stool and blood samples will be analyzed before and after the six week course of probiotics.
Interventions
- DIETARY_SUPPLEMENT VSL#3
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2018-04-23 |
| Est. Completion | 2018-12-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03423589
The ClinicalTrials.gov registry entry for NCT03423589 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medical College of Wisconsin, which has 447 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which VSL#3 is the first listed.
NCT03423589 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03423589 about?
NCT03423589 is a clinical study titled "Modulation of Type 1 Diabetes Susceptibility Through the Use of Probiotics". Investigators aim to further the understanding of environmental factors that underlie the progression to Type 1 diabetes (T1D). Dysbiosis, defined as alterations in intestinal microbiota composition and function, has been hypothesized to increase the risk of developing T1D in those with genetic susc...
What is the current status of trial NCT03423589?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2018-04-23. Estimated completion is 2018-12-31.
What interventions are being tested in trial NCT03423589?
The interventions under investigation include: VSL#3 (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT03423589?
This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.
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