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NCT03419195 · ClinicalTrials.gov registry record · NA
Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of Sex
A NA study, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- NA
- Development phase
- 124
- Enrollment target
NCT03419195: Completed NA study, sponsored by University of Colorado, Denver.
NCT03419195 is a NA study that has completed, run by University of Colorado, Denver. The registered enrollment target is 124 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03419195, a NA study, has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- NA
- Development phase
- 124 participants
- Enrollment target
Study Summary
This study will define the relationship of cardiac, vascular function and skeletal muscle blood flow (individually and together) to cardiovascular exercise capacity in in men and women with and without type 2 diabetes (T2DM). Identification of differences in the effects of exercise training on the integrated cardiovascular system and metabolism in men and women with and without T2DM will reveal specific adaptive responses to exercise.This study will evaluate \& compare exercise function in a total of 60 subjects from the Denver area (30 people with T2DM and 30 overweight control subjects). Specific Aim 1: To test the hypothesis that the integration of cardiac function, macrovascular function, and microvascular function is impaired in T2D and correlates with cardiovascular exercise capacity (CVEC) impairment. Specific Aim 2: To test the hypothesis that exercise training will elicit adaptive responses in cardiac and vascular function, muscle perfusion and metabolism with differences by T2D status. Differences between the exercise responses in people with T2DM and healthy people will help further identify the disease process of T2DM and direct future research of treatments and interventions.
Primary Outcome
Subjects' peak oxygen consumption will be tested on a stationary bike before and after 3 months of exercise
Interventions
- OTHER Cardiovascular exercise training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 124 participants |
| Start Date | 2018-02-07 |
| Est. Completion | 2023-03-20 |
| Phase | NA |
What the finished NCT03419195 record still lists
NCT03419195 is an interventional study that assigns participants to a tested intervention. The registered 124 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (91% lower).
The record links to 0 conditions, and to 1 intervention - of which Cardiovascular exercise training is the first listed.
NCT03419195 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03419195 about?
NCT03419195 is a clinical study titled "Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of Sex". This study will define the relationship of cardiac, vascular function and skeletal muscle blood flow (individually and together) to cardiovascular exercise capacity in in men and women with and without type 2 diabetes (T2DM). Identification of differences in the effects of exercise training on the i...
What is the current status of trial NCT03419195?
This trial is currently completed. It is a NA study. The enrollment target is 124 participants. The study started on 2018-02-07. Estimated completion is 2023-03-20.
What interventions are being tested in trial NCT03419195?
The interventions under investigation include: Cardiovascular exercise training (OTHER).
Who is sponsoring clinical trial NCT03419195?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03419195's enrollment target sits among peer trials
124 758th of 2000 higher than 1,239 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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