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NCT03418714 · ClinicalTrials.gov registry record · Phase 1
Effects of Salvinorin A on Brain Function
A Phase 1 study, sponsored by Johns Hopkins University.
- Completed
- Registry status
- Phase 1
- Development phase
- 13
- Enrollment target
NCT03418714: Completed Phase 1 study, sponsored by Johns Hopkins University.
NCT03418714 is a Phase 1 study that has completed, run by Johns Hopkins University. The registered enrollment target is 13 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (78% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03418714, a Phase 1 study, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 13 participants
- Enrollment target
Study Summary
This study will investigate the effects of salvinorin A on human brain activity and connectivity using functional magnetic resonance imaging (fMRI) methods. An inhalation route of administration will be used as it is the most common route for contemporary use of Salvia divinorum, a plant containing salvinorin A.
Primary Outcome
Changes in brain activity from before to after salvinorin A administration within canonical brain networks \[medial frontal (MF), frontoparietal (FP), default mode (DM), subcortical-cerebellum (SubC), somatosensory-motor (SM), medial visual (MedV), occipital pole (OccP), and lateral visual or (LatV)\] will be assessed using blood-oxygenation level dependent (BOLD) techniques. Due to salvinorin A's potential confounding influence on blood flow, activity was assessed by looking at the variance in
Interventions
- DRUG Salvinorin A
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2017-12-14 |
| Est. Completion | 2020-03-02 |
| Phase | Phase 1 |
What the finished NCT03418714 record still lists
NCT03418714 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (78% lower).
The record links to 0 conditions, and to 1 intervention - of which Salvinorin A is the first listed.
NCT03418714 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03418714 about?
NCT03418714 is a clinical study titled "Effects of Salvinorin A on Brain Function". This study will investigate the effects of salvinorin A on human brain activity and connectivity using functional magnetic resonance imaging (fMRI) methods. An inhalation route of administration will be used as it is the most common route for contemporary use of Salvia divinorum, a plant containing ...
What is the current status of trial NCT03418714?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 13 participants. The study started on 2017-12-14. Estimated completion is 2020-03-02.
What interventions are being tested in trial NCT03418714?
The interventions under investigation include: Salvinorin A (DRUG).
Who is sponsoring clinical trial NCT03418714?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03418714's enrollment target sits among peer trials
13 1847th of 2000 higher than 149 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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