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NCT03413657 · ClinicalTrials.gov registry record · NA
Predicting Fluid Responsiveness Using Transiently Increased Intrathoracic Pressure in Mechanically Ventilated Patients
A NA study, sponsored by University of California, Davis.
- Completed
- Registry status
- NA
- Development phase
- 5
- Enrollment target
NCT03413657 is a NA study that has completed, run by University of California, Davis. The registered enrollment target is 5 participants.
The verdict
NCT03413657, a NA study, has completed, sponsored by University of California, Davis.
- COMPLETED
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
Study Summary
The goal of this study is to identify in patients requiring active fluid resuscitation and mechanical ventilation for circulatory shock, can a controlled increase in intrathoracic pressure (either by positive-end expiratory pressure (PEEP) or tidal volume (TV)) predict responsiveness to additional fluid resuscitation. We hypothesize that a temporary, physiologically-safe increase in positive-end expiratory pressure (PEEP) and/or a temporary increase in tidal volume (from 6 cc/kg predicted body weight (PBW) to 8 cc/kg PBW) in patients requiring invasive mechanical ventilation will predict fluid responsiveness based upon an assessment of the change in pulse pressure and stroke volume variation.
Interventions
- PROCEDURE Increase in intrathoracic pressure
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2017-12-27 |
| Est. Completion | 2018-09-13 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03413657
The ClinicalTrials.gov registry entry for NCT03413657 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Increase in intrathoracic pressure is the first listed.
NCT03413657 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03413657 about?
NCT03413657 is a clinical study titled "Predicting Fluid Responsiveness Using Transiently Increased Intrathoracic Pressure in Mechanically Ventilated Patients". The goal of this study is to identify in patients requiring active fluid resuscitation and mechanical ventilation for circulatory shock, can a controlled increase in intrathoracic pressure (either by positive-end expiratory pressure (PEEP) or tidal volume (TV)) predict responsiveness to additional f...
What is the current status of trial NCT03413657?
This trial is currently completed. It is a NA study. The enrollment target is 5 participants. The study started on 2017-12-27. Estimated completion is 2018-09-13.
What interventions are being tested in trial NCT03413657?
The interventions under investigation include: Increase in intrathoracic pressure (PROCEDURE).
Who is sponsoring clinical trial NCT03413657?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
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