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NCT03411681 · ClinicalTrials.gov registry record · NA
Resistance Exercise and Muscle Protein Synthesis in Obese Adults
A NA study, sponsored by University of Illinois at Urbana-Champaign.
- Completed
- Registry status
- NA
- Development phase
- 19
- Enrollment target
NCT03411681: Completed NA study, sponsored by University of Illinois at Urbana-Champaign.
NCT03411681 is a NA study that has completed, run by University of Illinois at Urbana-Champaign. The registered enrollment target is 19 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03411681, a NA study, has completed, sponsored by University of Illinois at Urbana-Champaign.
- COMPLETED
- Registry status
- NA
- Development phase
- 19 participants
- Enrollment target
Study Summary
Obesity has numerous comorbidities that are associated with exceedingly high healthcare costs. In addition to well- characterized impairments in lipid and glucose metabolism, obesity is associated with altered protein metabolism. We have recently observed that obese individuals are essentially nonresponsive to protein ingestion with respect to myofibrillar protein synthesis. This suggests that skeletal muscle remodeling in obese individuals is impaired possibly contributing to a poor metabolic quality of muscle. Resistance exercise is known to strongly augment muscle protein synthesis in response to protein ingestion. The purpose of this research is to determine the muscle protein synthetic response during post-exercise recovery in obese individuals. Using stable isotope methodology, we will determine the postprandial muscle protein synthetic response in 14 male and female obese adults (Age: 20-45, BMI: 30-39.9 kg/m2) immediately after an acute bout of resistance exercise. Participants will be sedentary (\< 60 min exercise/ week) and weight stable for a minimum of 6 months. During the testing blood and muscle samples will be collected. In addition participants will be asked to perform moderate intensity resistance exercise. Completion of the proposed research will identify the role of resistance exercise in the maintenance of skeletal muscle tissue after the consumption of a protein-dense meal in obese people.
Primary Outcome
Fractional synthesis rate of myofibrillar proteins
Interventions
- OTHER Resistance Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2017-01-01 |
| Est. Completion | 2018-05-01 |
| Phase | NA |
What the finished NCT03411681 record still lists
NCT03411681 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Resistance Exercise is the first listed.
NCT03411681 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03411681 about?
NCT03411681 is a clinical study titled "Resistance Exercise and Muscle Protein Synthesis in Obese Adults". Obesity has numerous comorbidities that are associated with exceedingly high healthcare costs. In addition to well- characterized impairments in lipid and glucose metabolism, obesity is associated with altered protein metabolism. We have recently observed that obese individuals are essentially nonre...
What is the current status of trial NCT03411681?
This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 2017-01-01. Estimated completion is 2018-05-01.
What interventions are being tested in trial NCT03411681?
The interventions under investigation include: Resistance Exercise (OTHER).
Who is sponsoring clinical trial NCT03411681?
This trial is sponsored by University of Illinois at Urbana-Champaign, which has 129 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03411681's enrollment target sits among peer trials
19 1861st of 2000 higher than 138 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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