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NCT03411681 · ClinicalTrials.gov registry record · NA
Resistance Exercise and Muscle Protein Synthesis in Obese Adults
A NA study, sponsored by University of Illinois at Urbana-Champaign.
- Completed
- Registry status
- NA
- Development phase
- 19
- Enrollment target
NCT03411681 is a NA study that has completed, run by University of Illinois at Urbana-Champaign. The registered enrollment target is 19 participants.
The verdict
NCT03411681, a NA study, has completed, sponsored by University of Illinois at Urbana-Champaign.
- COMPLETED
- Registry status
- NA
- Development phase
- 19 participants
- Enrollment target
Study Summary
Obesity has numerous comorbidities that are associated with exceedingly high healthcare costs. In addition to well- characterized impairments in lipid and glucose metabolism, obesity is associated with altered protein metabolism. We have recently observed that obese individuals are essentially nonresponsive to protein ingestion with respect to myofibrillar protein synthesis. This suggests that skeletal muscle remodeling in obese individuals is impaired possibly contributing to a poor metabolic quality of muscle. Resistance exercise is known to strongly augment muscle protein synthesis in response to protein ingestion. The purpose of this research is to determine the muscle protein synthetic response during post-exercise recovery in obese individuals. Using stable isotope methodology, we will determine the postprandial muscle protein synthetic response in 14 male and female obese adults (Age: 20-45, BMI: 30-39.9 kg/m2) immediately after an acute bout of resistance exercise. Participants will be sedentary (\< 60 min exercise/ week) and weight stable for a minimum of 6 months. During the testing blood and muscle samples will be collected. In addition participants will be asked to perform moderate intensity resistance exercise. Completion of the proposed research will identify the role of resistance exercise in the maintenance of skeletal muscle tissue after the consumption of a protein-dense meal in obese people.
Interventions
- OTHER Resistance Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2017-01-01 |
| Est. Completion | 2018-05-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03411681
The ClinicalTrials.gov registry entry for NCT03411681 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Illinois at Urbana-Champaign, which has 129 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Resistance Exercise is the first listed.
NCT03411681 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03411681 about?
NCT03411681 is a clinical study titled "Resistance Exercise and Muscle Protein Synthesis in Obese Adults". Obesity has numerous comorbidities that are associated with exceedingly high healthcare costs. In addition to well- characterized impairments in lipid and glucose metabolism, obesity is associated with altered protein metabolism. We have recently observed that obese individuals are essentially nonre...
What is the current status of trial NCT03411681?
This trial is currently completed. It is a NA study. The enrollment target is 19 participants. The study started on 2017-01-01. Estimated completion is 2018-05-01.
What interventions are being tested in trial NCT03411681?
The interventions under investigation include: Resistance Exercise (OTHER).
Who is sponsoring clinical trial NCT03411681?
This trial is sponsored by University of Illinois at Urbana-Champaign, which has 129 total clinical trials registered on ClinicalTrials.gov.
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