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NCT03405142 · ClinicalTrials.gov registry record · Phase 2
Panitumumab-IRDye800 Compared to Sentinel Node Biopsy and (Selective) Neck Dissection in Identifying Metastatic Lymph Nodes in Patients With Head&Neck Cancer
A Phase 2 study, sponsored by Eben Rosenthal.
- Completed
- Registry status
- Phase 2
- Development phase
- 3
- Enrollment target
NCT03405142: Completed Phase 2 study, sponsored by Eben Rosenthal.
NCT03405142 is a Phase 2 study that has completed, run by Eben Rosenthal. The registered enrollment target is 3 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03405142, a Phase 2 study, has completed, sponsored by Eben Rosenthal.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 3 participants
- Enrollment target
Study Summary
This phase 2 trial studies how well panitumumab-IRDye800 works in identifying head and neck cancer that has spread to the lymph nodes in patients with head and neck cancer. Panitumumab-IRDye800 may help surgeons to identify metastatic lymph nodes during surgical removal of the primary tumor and/or lymph nodes of the neck with equal or better accuracy than the current methods.
Primary Outcome
After administration of panitumumab-IRDye800 alone or with Lymphoseek, lymph nodes potentially containing malignant tumor cells were surgically removed, and the lymph node tissue was evaluated for panitumumab-IRDye800 fluorescence intensity. For each subject, the 5 lymph nodes with the strongest fluorescence signal were tabulated against the Lymphoseek and histopathologic findings for those specific lymph nodes. For each of the 3 modalities, a positive finding is considered indicative of maligna
Interventions
- DRUG Panitumumab-IRDye800
- DRUG Lymphoseek
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2019-08-01 |
| Est. Completion | 2021-04-27 |
| Phase | Phase 2 |
What the finished NCT03405142 record still lists
NCT03405142 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Panitumumab-IRDye800 is the first listed.
NCT03405142 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03405142 about?
NCT03405142 is a clinical study titled "Panitumumab-IRDye800 Compared to Sentinel Node Biopsy and (Selective) Neck Dissection in Identifying Metastatic Lymph Nodes in Patients With Head&Neck Cancer". This phase 2 trial studies how well panitumumab-IRDye800 works in identifying head and neck cancer that has spread to the lymph nodes in patients with head and neck cancer. Panitumumab-IRDye800 may help surgeons to identify metastatic lymph nodes during surgical removal of the primary tumor and/or l...
What is the current status of trial NCT03405142?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 3 participants. The study started on 2019-08-01. Estimated completion is 2021-04-27.
What interventions are being tested in trial NCT03405142?
The interventions under investigation include: Panitumumab-IRDye800 (DRUG), Lymphoseek (DRUG).
Who is sponsoring clinical trial NCT03405142?
This trial is sponsored by Eben Rosenthal, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03405142's enrollment target sits among peer trials
3 2001st of 2000 the lowest of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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