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NCT03396978 · ClinicalTrials.gov registry record · NA
The Influence of Gonadal Hormone Suppression on Adipocyte Lineage and the Microbiome
A NA study, sponsored by University of Colorado, Denver.
- Terminated
- Registry status
- NA
- Development phase
- 5
- Enrollment target
NCT03396978 is a NA study that was terminated before completion, run by University of Colorado, Denver. The registered enrollment target is 5 participants.
The verdict
NCT03396978, a NA study, was terminated before completion, sponsored by University of Colorado, Denver.
- TERMINATED
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
Study Summary
This research study plans to learn more about the role of female sex hormones on adipose tissue (or fat) and the gut microbiome (or the organisms that are in your digestive tract). The rationale for this study is that the rate at which women gain fat (especially in the stomach region) increases after menopause. It is thought to be due to the loss of estrogen because post-menopausal women who take estrogen gain less weight than those who do not take estrogen. Gut bacteria process estrogen and help determine the types of estrogen that circulate in the body. These bacteria can be changed with lifestyle factors such as diet, and may therefore, also affect the risk of diseases that are more common in women after menopause i.e., cardiovascular disease and cancer. In this study the investigators will obtain fat biopsies before and after 6 months of ovarian hormone suppression to measure how the fat cells change with the loss of female sex hormones (e.g., medical menopause). The investigators will also obtain stool and urine samples before and every month during the study to measure changes in the microbiome.
Interventions
- OTHER GnRHag
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2018-01-11 |
| Est. Completion | 2019-12-18 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03396978
The ClinicalTrials.gov registry entry for NCT03396978 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which GnRHag is the first listed.
NCT03396978 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03396978 about?
NCT03396978 is a clinical study titled "The Influence of Gonadal Hormone Suppression on Adipocyte Lineage and the Microbiome". This research study plans to learn more about the role of female sex hormones on adipose tissue (or fat) and the gut microbiome (or the organisms that are in your digestive tract). The rationale for this study is that the rate at which women gain fat (especially in the stomach region) increases afte...
What is the current status of trial NCT03396978?
This trial is currently terminated. It is a NA study. The enrollment target is 5 participants. The study started on 2018-01-11. Estimated completion is 2019-12-18.
What interventions are being tested in trial NCT03396978?
The interventions under investigation include: GnRHag (OTHER).
Who is sponsoring clinical trial NCT03396978?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
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