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NCT03395184 · ClinicalTrials.gov registry record · Phase 2

Study To Evaluate The Efficacy And Safety Of Oral PF-06651600 And PF-06700841 In Subjects With Moderate To Severe Crohn's Disease

A Phase 2 study, sponsored by Pfizer.

Completed
Registry status
Phase 2
Development phase
244
Enrollment target

NCT03395184 is a Phase 2 study that has completed, run by Pfizer. The registered enrollment target is 244 participants.

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The verdict

NCT03395184, a Phase 2 study, has completed, sponsored by Pfizer.

COMPLETED
Registry status
Phase 2
Development phase
244 participants
Enrollment target

Study Summary

The objectives of this study are to evaluate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06651600 (200 mg for 8 weeks followed by 50 mg for 4 weeks) dosed once daily and PF-06700841 (60 mg for 12 weeks) dosed once daily during an induction period of 12 weeks, followed by an open label extension period at doses of 50 mg and 30 mg of PF 06651600 and PF 06700841, respectively, for 52 weeks.

Interventions

  • DRUG PF-06651600
  • DRUG PF-06700841
  • DRUG PF-06651600 Placebo
  • DRUG Placebo PF-06700841

Trial Details

FieldValue
Enrollment Target 244 participants
Start Date 2018-02-02
Est. Completion 2023-10-19
Phase Phase 2

Sponsor

Pfizer

1,845 total trials

What the Registry Record Tells You About NCT03395184

The ClinicalTrials.gov registry entry for NCT03395184 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 244 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Pfizer, which has 1,845 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which PF-06651600 is the first listed.

NCT03395184 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03395184 about?

NCT03395184 is a clinical study titled "Study To Evaluate The Efficacy And Safety Of Oral PF-06651600 And PF-06700841 In Subjects With Moderate To Severe Crohn's Disease". The objectives of this study are to evaluate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06651600 (200 mg for 8 weeks followed by 50 mg for 4 weeks) dosed once daily and PF-06700841 (60 mg for 12 weeks) dosed once daily during an induction period of 12 weeks, fol...

What is the current status of trial NCT03395184?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 244 participants. The study started on 2018-02-02. Estimated completion is 2023-10-19.

What interventions are being tested in trial NCT03395184?

The interventions under investigation include: PF-06651600 (DRUG), PF-06700841 (DRUG), PF-06651600 Placebo (DRUG), Placebo PF-06700841 (DRUG).

Who is sponsoring clinical trial NCT03395184?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.