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NCT03394066 · ClinicalTrials.gov registry record · NA
Mechanism of Non-invasive Magnetic Stimulation
A NA study of Healthy Volunteers, sponsored by National Institute on Drug Abuse (NIDA).
- Recruiting
- Registry status
- NA
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT03394066: Recruiting NA study of Healthy Volunteers, sponsored by National Institute on Drug Abuse (NIDA).
NCT03394066 is a NA study of Healthy Volunteers that is actively recruiting participants, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 70 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03394066, a NA study of Healthy Volunteers, is actively recruiting participants, sponsored by National Institute on Drug Abuse (NIDA).
- RECRUITING
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Transcranial magnetic stimulation (TMS) is form of non-invasive brain stimulation. It is approved to treat depression. TMS may help decrease drug craving. It is important to understand how TMS affects the brain. Such a better understanding would help to design ways to treat drug addiction. Objectives: To learn how TMS affects the brain when it stimulates an area in the front of the brain. Also, to see how the stimulation affects the area stimulated and other connected areas. Eligibility: Healthy, right-handed adults ages 18-60 who are non-drug users. Design: Participants will be screened under protocol 06-DA-N415. Participants will have at least 3 visits. The first visit will last about 3 hours. All other visits will last up to 6 hours. Participants cannot use drugs or alcohol at least 24 hours before a visit. They cannot have more than half a cup of a caffeinated drink at least 12 hours before a visit. Each visit will include a brief medical history update, urine test for drugs and pregnancy (if female), a breath test for alcohol and smoking, and questionnaires. Participants will have a TMS orientation visit. A wire coil will be placed on the head. An electrical current will pass through the coil to create a magnetic pulse that stimulates the brain. The other visits will include 2 sessions of TMS-MRI. Participants will lie on a table that slides into a cylinder. The TMS coil and the MRI coil will be placed over the head. Pictures will be taken of the brain with and without stimulation. Participants will complete a questionnaire about how they feel before and after each TMS session and in a follow-up call 1-3 days after their last session.
Primary Outcome
fMRI blood oxygen level-dependent (BOLD) responses, TMS induced changes on resting state functional connectivity, and their associations with relevant structural connectivity revealed by DTI
Conditions Studied
Interventions
- DEVICE TMS (MagVenture MagPro 100 with MagOption)
Study Locations (1)
Maryland
- National Institute on Drug Abuse - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2018-09-19 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT03394066 shows while recruiting
NCT03394066 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 1 intervention - of which TMS (MagVenture MagPro 100 with MagOption) is the first listed.
NCT03394066 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT03394066 about?
NCT03394066 is a clinical study titled "Mechanism of Non-invasive Magnetic Stimulation". Background: Transcranial magnetic stimulation (TMS) is form of non-invasive brain stimulation. It is approved to treat depression. TMS may help decrease drug craving. It is important to understand how TMS affects the brain. Such a better understanding would help to design ways to treat drug addicti...
What is the current status of trial NCT03394066?
This trial is currently recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2018-09-19. Estimated completion is 2026-12-31.
What conditions does trial NCT03394066 study?
This clinical trial studies the following conditions: Healthy Volunteers.
What interventions are being tested in trial NCT03394066?
The interventions under investigation include: TMS (MagVenture MagPro 100 with MagOption) (DEVICE).
Who is sponsoring clinical trial NCT03394066?
This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03394066 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03394066's enrollment target sits among peer trials
70 95th of 283 higher than 187 of 283 other Healthy Volunteers trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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