Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03392974 · ClinicalTrials.gov registry record · Phase 3

Single-Arm Study To Evaluate The Efficacy and Safety of Valoctocogene Roxaparvovec in Hemophilia A Patients at a Dose of 4E13 vg/kg

A Phase 3 study, sponsored by BioMarin Pharmaceutical.

Completed
Registry status
Phase 3
Development phase
1
Enrollment target

NCT03392974 is a Phase 3 study that has completed, run by BioMarin Pharmaceutical. The registered enrollment target is 1 participants.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03392974, a Phase 3 study, has completed, sponsored by BioMarin Pharmaceutical.

COMPLETED
Registry status
Phase 3
Development phase
1 participants
Enrollment target

Study Summary

This Phase III clinical study will assess the efficacy of BMN 270 defined as FVIII activity, during weeks 49-52 following intravenous infusion of BMN 270 and assess the impact of BMN 270 on usage of exogenous FVIII replacement therapy and the number of bleeding episodes from week 5 to week 52.

Interventions

  • BIOLOGICAL Valoctocogene Roxaparvovec

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2018-03-14
Est. Completion 2023-06-05
Phase Phase 3

Sponsor

BioMarin Pharmaceutical

80 total trials

What the Registry Record Tells You About NCT03392974

The ClinicalTrials.gov registry entry for NCT03392974 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 1 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is BioMarin Pharmaceutical, which has 80 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Valoctocogene Roxaparvovec is the first listed.

NCT03392974 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03392974 about?

NCT03392974 is a clinical study titled "Single-Arm Study To Evaluate The Efficacy and Safety of Valoctocogene Roxaparvovec in Hemophilia A Patients at a Dose of 4E13 vg/kg". This Phase III clinical study will assess the efficacy of BMN 270 defined as FVIII activity, during weeks 49-52 following intravenous infusion of BMN 270 and assess the impact of BMN 270 on usage of exogenous FVIII replacement therapy and the number of bleeding episodes from week 5 to week 52.

What is the current status of trial NCT03392974?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 1 participants. The study started on 2018-03-14. Estimated completion is 2023-06-05.

What interventions are being tested in trial NCT03392974?

The interventions under investigation include: Valoctocogene Roxaparvovec (BIOLOGICAL).

Who is sponsoring clinical trial NCT03392974?

This trial is sponsored by BioMarin Pharmaceutical, which has 80 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.