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NCT03389971 · ClinicalTrials.gov registry record · NA
ULTRAsound-assisted Catheter vs. STAndaRd Catheter Thrombolysis for Submassive Pulmonary Embolism
A NA study, sponsored by Piedmont Healthcare.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT03389971: Completed NA study, sponsored by Piedmont Healthcare.
NCT03389971 is a NA study that has completed, run by Piedmont Healthcare. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03389971, a NA study, has completed, sponsored by Piedmont Healthcare.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
Acute pulmonary embolism (PE) accounts for 5-10% of in-hospital deaths. Systemic anticoagulation (AC) is the standard of care and thrombolysis is recommended for those at a higher mortality risk. Catheter-directed therapies, mainly standard infusion catheter thrombolysis (CDT) and ultrasound-accelerated thrombolysis (USAT), have been introduced as new more effective and safer treatment modalities. USAT is a modification of standard catheter lysis utilizing a system of local ultrasound to dissociate the fibrin matrix of the thrombus with simultaneous acoustic streaming of the thrombolytic agent, allowing more efficient thrombolysis. However, there is limited comparative effectiveness data against standard multi-side hole catheter infusion. More rapid clearance of pulmonary thrombus by USAT compared to standard CDT may prove to be clinically beneficial and cost effective. Alternatively, if thrombus clearance is similar, the cost of USAT may exceed the cost of CDT (equipment and disposables), without realization any advantage.
Primary Outcome
Determine differences in the percentage of thrombus load reduction from baseline to the termination of lysis between the two techniques
Interventions
- PROCEDURE catheter-directed thrombolysis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2017-12-06 |
| Est. Completion | 2020-04-01 |
| Phase | NA |
What the finished NCT03389971 record still lists
NCT03389971 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which catheter-directed thrombolysis is the first listed.
NCT03389971 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03389971 about?
NCT03389971 is a clinical study titled "ULTRAsound-assisted Catheter vs. STAndaRd Catheter Thrombolysis for Submassive Pulmonary Embolism". Acute pulmonary embolism (PE) accounts for 5-10% of in-hospital deaths. Systemic anticoagulation (AC) is the standard of care and thrombolysis is recommended for those at a higher mortality risk. Catheter-directed therapies, mainly standard infusion catheter thrombolysis (CDT) and ultrasound-acceler...
What is the current status of trial NCT03389971?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2017-12-06. Estimated completion is 2020-04-01.
What interventions are being tested in trial NCT03389971?
The interventions under investigation include: catheter-directed thrombolysis (PROCEDURE).
Who is sponsoring clinical trial NCT03389971?
This trial is sponsored by Piedmont Healthcare, which has 13 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03389971's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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