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NCT03386227 · ClinicalTrials.gov registry record · NA
Prophylactic Antibiotics Prior to Embryo Transfer (PAPET): RCT
A NA study, sponsored by Washington University School of Medicine.
- Terminated
- Registry status
- NA
- Development phase
- 96
- Enrollment target
NCT03386227: Clinical Trial NA study, sponsored by Washington University School of Medicine.
NCT03386227 is a NA study that was terminated before completion, run by Washington University School of Medicine. The registered enrollment target is 96 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03386227, a NA study, was terminated before completion, sponsored by Washington University School of Medicine.
- TERMINATED
- Registry status
- NA
- Development phase
- 96 participants
- Enrollment target
Study Summary
The objective of this study is to determine the impact on clinical pregnancy rate of withholding routine prophylactic antibiotic therapy during IVF. The hypothesis is that withholding antibiotic prophylaxis will be non-inferior to routine administration. To test this hypothesis, the investigators will conduct a randomized controlled non inferiority trial. Additionally an exploratory study will be conducted among the first 30 patients undergoing their first cycle enrolled to evaluate the microbiome across the IVF cycle, in addition to the human virome
Primary Outcome
Defined as a gestational sac, with fetal pole and cardiac activity, on ultrasound
Interventions
- OTHER Withholding antibiotic prophylaxis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 96 participants |
| Start Date | 2018-01-21 |
| Est. Completion | 2019-07-31 |
| Phase | NA |
Why NCT03386227 stopped before completion
NCT03386227 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 96 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 1 intervention - of which Withholding antibiotic prophylaxis is the first listed.
NCT03386227 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03386227 about?
NCT03386227 is a clinical study titled "Prophylactic Antibiotics Prior to Embryo Transfer (PAPET): RCT". The objective of this study is to determine the impact on clinical pregnancy rate of withholding routine prophylactic antibiotic therapy during IVF. The hypothesis is that withholding antibiotic prophylaxis will be non-inferior to routine administration. To test this hypothesis, the investigators wi...
What is the current status of trial NCT03386227?
This trial is currently terminated. It is a NA study. The enrollment target is 96 participants. The study started on 2018-01-21. Estimated completion is 2019-07-31.
What interventions are being tested in trial NCT03386227?
The interventions under investigation include: Withholding antibiotic prophylaxis (OTHER).
Who is sponsoring clinical trial NCT03386227?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03386227's enrollment target sits among peer trials
96 925th of 2000 higher than 1,070 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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