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NCT03381599 · ClinicalTrials.gov registry record · Phase 1

Stem Cells After Peripheral Mobilization and Harvest

A Phase 1 study, sponsored by Andrews Research & Education Foundation.

Completed
Registry status
Phase 1
Development phase
10
Enrollment target

NCT03381599: Completed Phase 1 study, sponsored by Andrews Research & Education Foundation.

NCT03381599 is a Phase 1 study that has completed, run by Andrews Research & Education Foundation. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03381599, a Phase 1 study, has completed, sponsored by Andrews Research & Education Foundation.

COMPLETED
Registry status
Phase 1
Development phase
10 participants
Enrollment target

Study Summary

The proposed study is a controlled laboratory study where stem cell content of bone marrow aspirate will be compared prior to and following pharmaceutical mobilization. Participants who meet the inclusion/exclusion criteria will have a bone marrow sample taken from the iliac crest. The sample will be tested to determine stem cell content and for the presence of proteins which are of interest in orthopedic treatments. Thirty days following the baseline bone marrow collection, participants will receive a subcutaneous injection of Filgrastim daily for four serial days. On the fifth day, a peripheral blood sample will be taken and processed.

Primary Outcome

Quantity and quality of the harvested stem cells

Interventions

  • DRUG Filgrastim Injection

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2018-03-28
Est. Completion 2019-09-04
Phase Phase 1

What the finished NCT03381599 record still lists

NCT03381599 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 1 intervention - of which Filgrastim Injection is the first listed.

NCT03381599 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03381599 about?

NCT03381599 is a clinical study titled "Stem Cells After Peripheral Mobilization and Harvest". The proposed study is a controlled laboratory study where stem cell content of bone marrow aspirate will be compared prior to and following pharmaceutical mobilization. Participants who meet the inclusion/exclusion criteria will have a bone marrow sample taken from the iliac crest. The sample will b...

What is the current status of trial NCT03381599?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2018-03-28. Estimated completion is 2019-09-04.

What interventions are being tested in trial NCT03381599?

The interventions under investigation include: Filgrastim Injection (DRUG).

Who is sponsoring clinical trial NCT03381599?

This trial is sponsored by Andrews Research & Education Foundation, which has 10 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03381599's enrollment target sits among peer trials

10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03381599, the US trial registry maintained by the National Library of Medicine. NCT03381599 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.