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NCT03376841 · ClinicalTrials.gov registry record · Phase 1
Impact of Severe Hepatic Impairment on Pharmacokinetics of Cenicriviroc and Its Metabolites
A Phase 1 study, sponsored by Allergan.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT03376841: Completed Phase 1 study, sponsored by Allergan.
NCT03376841 is a Phase 1 study that has completed, run by Allergan. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03376841, a Phase 1 study, has completed, sponsored by Allergan.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
The objective of this study is to assess the pharmacokinetics (PK), safety, and tolerability profiles of cenicriviroc (CVC) and its metabolites (M-I and M-II) in participants with severely impaired hepatic function compared with matched healthy participants following single-dose administration
Interventions
- DRUG Cenicriviroc
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2017-06-06 |
| Est. Completion | 2017-12-17 |
| Phase | Phase 1 |
What the finished NCT03376841 record still lists
NCT03376841 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 1 intervention - of which Cenicriviroc is the first listed.
NCT03376841 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03376841 about?
NCT03376841 is a clinical study titled "Impact of Severe Hepatic Impairment on Pharmacokinetics of Cenicriviroc and Its Metabolites". The objective of this study is to assess the pharmacokinetics (PK), safety, and tolerability profiles of cenicriviroc (CVC) and its metabolites (M-I and M-II) in participants with severely impaired hepatic function compared with matched healthy participants following single-dose administration
What is the current status of trial NCT03376841?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2017-06-06. Estimated completion is 2017-12-17.
What interventions are being tested in trial NCT03376841?
The interventions under investigation include: Cenicriviroc (DRUG).
Who is sponsoring clinical trial NCT03376841?
This trial is sponsored by Allergan, which has 314 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03376841's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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