Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03375294 · ClinicalTrials.gov registry record · Phase 2

Exploring Nitrous Oxide Effects for Post Traumatic Stress Disorder (PTSD)

A Phase 2 study, sponsored by Stanford University.

Completed
Registry status
Phase 2
Development phase
3
Enrollment target

NCT03375294: Completed Phase 2 study, sponsored by Stanford University.

NCT03375294 is a Phase 2 study that has completed, run by Stanford University. The registered enrollment target is 3 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist → Add completion date to calendar (.ics) →

The verdict

NCT03375294, a Phase 2 study, has completed, sponsored by Stanford University.

COMPLETED
Registry status
Phase 2
Development phase
3 participants
Enrollment target

Study Summary

The purpose of this study is to understand nitrous oxide effects in post traumatic stress disorder (PTSD)

Primary Outcome

Patients given CAPS-5 (Clinician Administered PTSD Scale for DSM-5), a 30-item structured interview that can be used to assess PTSD symptoms over the past week. For the CAPS-5 the minimum units are 0 and maximum units on the total scale are 80. The higher the number on the CAPS-5, the more severe the symptoms. Response was defined as at least a 12 point reduction on the CAPS-5

Interventions

  • DRUG Nitrous Oxide

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2018-04-01
Est. Completion 2020-04-05
Phase Phase 2
Stanford University

1,744 total trials

What the finished NCT03375294 record still lists

NCT03375294 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which Nitrous Oxide is the first listed.

NCT03375294 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03375294 about?

NCT03375294 is a clinical study titled "Exploring Nitrous Oxide Effects for Post Traumatic Stress Disorder (PTSD)". The purpose of this study is to understand nitrous oxide effects in post traumatic stress disorder (PTSD)

What is the current status of trial NCT03375294?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 3 participants. The study started on 2018-04-01. Estimated completion is 2020-04-05.

What interventions are being tested in trial NCT03375294?

The interventions under investigation include: Nitrous Oxide (DRUG).

Who is sponsoring clinical trial NCT03375294?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03375294's enrollment target sits among peer trials

3 2001st of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03375294, the US trial registry maintained by the National Library of Medicine. NCT03375294 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.