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NCT03373981 · ClinicalTrials.gov registry record · NA
Non-invasive Brain Stimulation for the Treatment of Depression Symptoms in ALS
A NA study, sponsored by Hospital for Special Surgery, New York.
- Terminated
- Registry status
- NA
- Development phase
- 3
- Enrollment target
NCT03373981: Clinical Trial NA study, sponsored by Hospital for Special Surgery, New York.
NCT03373981 is a NA study that was terminated before completion, run by Hospital for Special Surgery, New York. The registered enrollment target is 3 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03373981, a NA study, was terminated before completion, sponsored by Hospital for Special Surgery, New York.
- TERMINATED
- Registry status
- NA
- Development phase
- 3 participants
- Enrollment target
Study Summary
This is an open-label clinical trial to determine the safety of rTMS and efficacy in improving depression symptoms, quality of life and cognition deficits among patients with Amyotrophic Lateral Sclerosis (ALS) and other neurodegenerative disorders.
Primary Outcome
Transcranial magnetic stimulation (TMS) is a non-invasive procedure used to stimulate small regions of the brain. It is a FDA approved for treatment resistant depression (K061053). We hypothesize that stimulation of dorsolateral prefrontal cortex (DLPFC) will be safe and effective in patients with ALS and other Neurodegenerative disorders. We will follow the FDA rTMS guidance for industry guidelines. All adverse events from all 15 patients enrolled in the study as assessed by the CTCAE v4.0, and
Interventions
- DEVICE rTMS
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2017-11-29 |
| Est. Completion | 2022-08-16 |
| Phase | NA |
Why NCT03373981 stopped before completion
NCT03373981 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which rTMS is the first listed.
NCT03373981 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03373981 about?
NCT03373981 is a clinical study titled "Non-invasive Brain Stimulation for the Treatment of Depression Symptoms in ALS". This is an open-label clinical trial to determine the safety of rTMS and efficacy in improving depression symptoms, quality of life and cognition deficits among patients with Amyotrophic Lateral Sclerosis (ALS) and other neurodegenerative disorders.
What is the current status of trial NCT03373981?
This trial is currently terminated. It is a NA study. The enrollment target is 3 participants. The study started on 2017-11-29. Estimated completion is 2022-08-16.
What interventions are being tested in trial NCT03373981?
The interventions under investigation include: rTMS (DEVICE).
Who is sponsoring clinical trial NCT03373981?
This trial is sponsored by Hospital for Special Surgery, New York, which has 194 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03373981's enrollment target sits among peer trials
3 1996th of 2000 higher than 4 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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