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NCT03371823 · ClinicalTrials.gov registry record · Phase 4
Vascular Dysfunction in Hypertensive Postmenopausal Women
A Phase 4 study, sponsored by University of Delaware.
- Terminated
- Registry status
- Phase 4
- Development phase
- 8
- Enrollment target
NCT03371823: Clinical Trial Phase 4 study, sponsored by University of Delaware.
NCT03371823 is a Phase 4 study that was terminated before completion, run by University of Delaware. The registered enrollment target is 8 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03371823, a Phase 4 study, was terminated before completion, sponsored by University of Delaware.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 8 participants
- Enrollment target
Study Summary
The purpose of this study is to investigate the role of ET-1 in mediating vasoconstrictor tone in hypertensive postmenopausal women (PMW) alone and in combination with a commonly prescribed Angiotensin II (ANG II) antagonist. The long term goal is to understand the mechanisms contributing to hypertension (HTN) in PMW. This study is the first step in reaching our goal.
Primary Outcome
Cutaneous blood flow is measured via laser Doppler flowmetry during cutaneous microdialysis perfusions of ET-A and ET-B receptor antagonists as previously described by Wenner MM in 2017(see reference list).
Interventions
- OTHER Normotensive
- DRUG Hypertensives
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2017-09-01 |
| Est. Completion | 2019-12-31 |
| Phase | Phase 4 |
Why NCT03371823 stopped before completion
NCT03371823 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Normotensive is the first listed.
NCT03371823 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03371823 about?
NCT03371823 is a clinical study titled "Vascular Dysfunction in Hypertensive Postmenopausal Women". The purpose of this study is to investigate the role of ET-1 in mediating vasoconstrictor tone in hypertensive postmenopausal women (PMW) alone and in combination with a commonly prescribed Angiotensin II (ANG II) antagonist. The long term goal is to understand the mechanisms contributing to hyperte...
What is the current status of trial NCT03371823?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 8 participants. The study started on 2017-09-01. Estimated completion is 2019-12-31.
What interventions are being tested in trial NCT03371823?
The interventions under investigation include: Normotensive (OTHER), Hypertensives (DRUG).
Who is sponsoring clinical trial NCT03371823?
This trial is sponsored by University of Delaware, which has 106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03371823's enrollment target sits among peer trials
8 1972nd of 2000 higher than 20 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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