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NCT03367715 · ClinicalTrials.gov registry record · Phase 2
Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma
A Phase 2 study, sponsored by NYU Langone Health.
- Completed
- Registry status
- Phase 2
- Development phase
- 10
- Enrollment target
NCT03367715: Completed Phase 2 study, sponsored by NYU Langone Health.
NCT03367715 is a Phase 2 study that has completed, run by NYU Langone Health. The registered enrollment target is 10 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03367715, a Phase 2 study, has completed, sponsored by NYU Langone Health.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 10 participants
- Enrollment target
Study Summary
This is a single arm, open-label, phase II trial of nivolumab, ipilimumab and short-course radiation therapy in adult patients with newly diagnosed, MGMT unmethylated GBM with the primary objective of determining the overall survival at 1 year.
Primary Outcome
Survival rate is defined as the percentage of participants who survived at 1 year (from either the date of diagnosis or the start of treatment for a disease)
Interventions
- DRUG Nivolumab
- DRUG Ipilimumab
- RADIATION Radiation Therapy (RT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2018-02-07 |
| Est. Completion | 2022-03-17 |
| Phase | Phase 2 |
What the finished NCT03367715 record still lists
NCT03367715 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 3 interventions - of which Nivolumab is the first listed.
NCT03367715 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03367715 about?
NCT03367715 is a clinical study titled "Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma". This is a single arm, open-label, phase II trial of nivolumab, ipilimumab and short-course radiation therapy in adult patients with newly diagnosed, MGMT unmethylated GBM with the primary objective of determining the overall survival at 1 year.
What is the current status of trial NCT03367715?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 10 participants. The study started on 2018-02-07. Estimated completion is 2022-03-17.
What interventions are being tested in trial NCT03367715?
The interventions under investigation include: Nivolumab (DRUG), Ipilimumab (DRUG), Radiation Therapy (RT) (RADIATION).
Who is sponsoring clinical trial NCT03367715?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03367715's enrollment target sits among peer trials
10 1968th of 2000 higher than 12 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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