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NCT03365752 · ClinicalTrials.gov registry record · Phase 2
Chloroprocaine Spinal for Outpatient Knee Surgery
A Phase 2 study, sponsored by Hospital for Special Surgery, New York.
- Terminated
- Registry status
- Phase 2
- Development phase
- 39
- Enrollment target
NCT03365752: Clinical Trial Phase 2 study, sponsored by Hospital for Special Surgery, New York.
NCT03365752 is a Phase 2 study that was terminated before completion, run by Hospital for Special Surgery, New York. The registered enrollment target is 39 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (71% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03365752, a Phase 2 study, was terminated before completion, sponsored by Hospital for Special Surgery, New York.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 39 participants
- Enrollment target
Study Summary
Outpatient knee surgeries with duration of less than one hour pose a challenge to the use of spinal anesthesia given that traditional agents remain in effect for 2-3 hours, thus creating a mismatch between length of surgery and anesthetic resolution. The investigators hypothesize that the use of chloroprocaine can combine the benefits of a short spinal anesthetic while avoiding the side effects of a general anesthetic, thus promoting earlier discharge.
Primary Outcome
Defined as duration from arrival in the post-anesthesia care unit (PACU0 to the time patient meets the discharge criteria from the post anesthesia discharge scoring system (PADSS) for home readiness after ambulatory surgery
Interventions
- DRUG Mepivacaine
- DRUG Chloroprocaine
- DRUG General Anesthetics
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 39 participants |
| Start Date | 2018-06-24 |
| Est. Completion | 2021-02-04 |
| Phase | Phase 2 |
Why NCT03365752 stopped before completion
NCT03365752 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (71% lower).
The record links to 0 conditions, and to 3 interventions - of which Mepivacaine is the first listed.
NCT03365752 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03365752 about?
NCT03365752 is a clinical study titled "Chloroprocaine Spinal for Outpatient Knee Surgery". Outpatient knee surgeries with duration of less than one hour pose a challenge to the use of spinal anesthesia given that traditional agents remain in effect for 2-3 hours, thus creating a mismatch between length of surgery and anesthetic resolution. The investigators hypothesize that the use of chl...
What is the current status of trial NCT03365752?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 39 participants. The study started on 2018-06-24. Estimated completion is 2021-02-04.
What interventions are being tested in trial NCT03365752?
The interventions under investigation include: Mepivacaine (DRUG), Chloroprocaine (DRUG), General Anesthetics (DRUG).
Who is sponsoring clinical trial NCT03365752?
This trial is sponsored by Hospital for Special Surgery, New York, which has 194 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03365752's enrollment target sits among peer trials
39 1459th of 2000 higher than 534 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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